SummaryBackgroundC. elegans male sexual behaviors include chemotaxis and response to hermaphrodites, backing, turning, vulva location, spicule insertion, and sperm transfer, culminating in cross-fertilization of hermaphrodite oocytes with male sperm. The LOV-1 and PKD-2 transient receptor potential polycystin (TRPP) complex localizes to ciliated endings of C. elegans male-specific sensory neurons and mediates several aspects of male mating behavior. TRPP complex ciliary localization and sensory function are evolutionarily conserved. A genetic screen for C. elegans mutants with PKD-2 ciliary localization (Cil) defects led to the isolation of a mutation in the cil-1 gene.ResultsHere, we report that a phosphoinositide (PI) 5-phosphatase, CIL-1...
AbstractDespite undergoing normal development and acquiring normal morphology and motility, mutation...
SummaryBackgroundSexual reproduction in animals requires the production of highly specialized motile...
The cilium is a protrusion of cell membrane. Both the protein and lipid contents of cilia are differ...
SummaryBackgroundC. elegans male sexual behaviors include chemotaxis and response to hermaphrodites,...
PKD-2 and LOV-1 are a putative mechanosensory transient receptor potential (TRP) channel-receptor po...
The investigation of Caenorhabditis elegans males and the male-specific sensory neurons required for...
In nature, chemical communication between animals is important for species survival. Finding a matin...
AbstractPhospholipase Cɛ (PLCɛ) is a novel class of phosphoinositide-specific PLC with unknown physi...
Ovulation in Caenorhabditis elegans requires inositol 1,4,5-triphosphate (IP3) signaling activated b...
Cilia serve as sensory devices in a diversity of organisms and their defects contribute to many huma...
AbstractBackground: Male mating behavior of the nematode Caenorhabditis elegans offers an intriguing...
The cilium both releases and binds to extracellular vesicles (EVs). EVs may be used by cells as a fo...
AbstractFertilization, a critical step in animal reproduction, is triggered by a series of specializ...
Cilia are endowed with membrane receptors, channels, and signaling components whose localization and...
Sperm activation, termed spermiogenesis in Caenorhabditis elegans, is defined by the transition of i...
AbstractDespite undergoing normal development and acquiring normal morphology and motility, mutation...
SummaryBackgroundSexual reproduction in animals requires the production of highly specialized motile...
The cilium is a protrusion of cell membrane. Both the protein and lipid contents of cilia are differ...
SummaryBackgroundC. elegans male sexual behaviors include chemotaxis and response to hermaphrodites,...
PKD-2 and LOV-1 are a putative mechanosensory transient receptor potential (TRP) channel-receptor po...
The investigation of Caenorhabditis elegans males and the male-specific sensory neurons required for...
In nature, chemical communication between animals is important for species survival. Finding a matin...
AbstractPhospholipase Cɛ (PLCɛ) is a novel class of phosphoinositide-specific PLC with unknown physi...
Ovulation in Caenorhabditis elegans requires inositol 1,4,5-triphosphate (IP3) signaling activated b...
Cilia serve as sensory devices in a diversity of organisms and their defects contribute to many huma...
AbstractBackground: Male mating behavior of the nematode Caenorhabditis elegans offers an intriguing...
The cilium both releases and binds to extracellular vesicles (EVs). EVs may be used by cells as a fo...
AbstractFertilization, a critical step in animal reproduction, is triggered by a series of specializ...
Cilia are endowed with membrane receptors, channels, and signaling components whose localization and...
Sperm activation, termed spermiogenesis in Caenorhabditis elegans, is defined by the transition of i...
AbstractDespite undergoing normal development and acquiring normal morphology and motility, mutation...
SummaryBackgroundSexual reproduction in animals requires the production of highly specialized motile...
The cilium is a protrusion of cell membrane. Both the protein and lipid contents of cilia are differ...