To promote their survival, intracellular pathogens must confront microbicidal activities induced by interferons. In this issue of Cell Host & Microbe, Fentress et al. show that Toxoplasma gondii evades intracellular killing by deploying a virulence determinant, ROP18, which acts by directly phosphorylating and disabling an IFN-γ-inducible immunity-related GTPase involved in pathogen clearance
The intracellular protozoan Toxoplasma gondii is well known for its skill at invading and living wit...
Antimicrobial proteins deliver a double punch that can destroy the Toxoplasma gondii parasite and it...
UnlabelledThe intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species ...
To promote their survival, intracellular pathogens must confront microbicidal activities induced by ...
SummaryMacrophages are specialized to detect and destroy intracellular microbes and yet a number of ...
Toxoplasma gondii is an obligate-intracellular parasite, which causes disease in immunocompromised i...
IFN-γ is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma gon...
SummaryPolymorphic rhoptry-secreted kinases (ROPs) are essential virulence factors of Toxoplasma gon...
IFN-gamma is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma...
The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host cell ...
Cytokine-activated macrophages restrain the replication of intracellular parasites and disrupt the i...
"Toxoplasma gondii is a widely spread parasite worldwide among warmblooded organisms thanks to its ...
SummaryInterferon-γ (IFN-γ) is essential for host defense against intracellular pathogens. Stimulati...
The obligate intracellular pathogen, Toxoplasma gondii, is adept at creating a safe niche within the...
The intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species globally. ...
The intracellular protozoan Toxoplasma gondii is well known for its skill at invading and living wit...
Antimicrobial proteins deliver a double punch that can destroy the Toxoplasma gondii parasite and it...
UnlabelledThe intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species ...
To promote their survival, intracellular pathogens must confront microbicidal activities induced by ...
SummaryMacrophages are specialized to detect and destroy intracellular microbes and yet a number of ...
Toxoplasma gondii is an obligate-intracellular parasite, which causes disease in immunocompromised i...
IFN-γ is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma gon...
SummaryPolymorphic rhoptry-secreted kinases (ROPs) are essential virulence factors of Toxoplasma gon...
IFN-gamma is a major cytokine that mediates resistance against the intracellular parasite Toxoplasma...
The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host cell ...
Cytokine-activated macrophages restrain the replication of intracellular parasites and disrupt the i...
"Toxoplasma gondii is a widely spread parasite worldwide among warmblooded organisms thanks to its ...
SummaryInterferon-γ (IFN-γ) is essential for host defense against intracellular pathogens. Stimulati...
The obligate intracellular pathogen, Toxoplasma gondii, is adept at creating a safe niche within the...
The intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species globally. ...
The intracellular protozoan Toxoplasma gondii is well known for its skill at invading and living wit...
Antimicrobial proteins deliver a double punch that can destroy the Toxoplasma gondii parasite and it...
UnlabelledThe intracellular parasite Toxoplasma gondii infects a wide variety of vertebrate species ...