The transcription factor IRF4 is known to be essential for differentiation of effector CD4+ T cell subsets. In this issue, Yao et al. (2013) identify IRF4 as a regulator of checkpoints in the final steps and maintenance of CD8+ T cell effector differentiation
The transcription factor IRF-4 is necessary for Th17 cell differentiation. In this issue of Immunity...
Memory T cells are largely heterogeneous. The molecular mechanisms at the basis of their effector fu...
<div><p>CD8<sup>+</sup> T cell exhaustion commonly occurs in chronic infections and cancers. During ...
SummaryUpon infection, CD8+ T cells undergo a stepwise process of early activation, expansion, and d...
Upon infection, CD8(+) T cells undergo a stepwise process of early activation, expansion, and differ...
© 2014 Dr. Kevin ManDuring immune responses T cells are subject to clonal competition, which leads t...
In response to acute virus infections, CD8(+) T cells differentiate to form a large population of sh...
CD8(+) T-cell functions are critical for preventing chronic viral infections by eliminating infected...
CD8+ T Zellen unterstützen die Beseitigung von Pathogenen und sind somit entscheidend bei der Bekämp...
CD8+ T cell differentiation is a complex process that requires integration of signals from the TCR, ...
Interferon regulatory factor 4 (IRF4) has critical roles in immune cell differentiation and function...
During chronic stimulation, CD8+ T cells acquire an exhausted phenotype characterized by expression ...
Interferon regulatory factor 4 (IRF4) has critical roles in immune cell differentiation and function...
During immune responses, T cells are subject to clonal competition, which leads to the predominant e...
TCR signal strength is critical for CD8+ T cell clonal expansion after antigen stimulation. Levels o...
The transcription factor IRF-4 is necessary for Th17 cell differentiation. In this issue of Immunity...
Memory T cells are largely heterogeneous. The molecular mechanisms at the basis of their effector fu...
<div><p>CD8<sup>+</sup> T cell exhaustion commonly occurs in chronic infections and cancers. During ...
SummaryUpon infection, CD8+ T cells undergo a stepwise process of early activation, expansion, and d...
Upon infection, CD8(+) T cells undergo a stepwise process of early activation, expansion, and differ...
© 2014 Dr. Kevin ManDuring immune responses T cells are subject to clonal competition, which leads t...
In response to acute virus infections, CD8(+) T cells differentiate to form a large population of sh...
CD8(+) T-cell functions are critical for preventing chronic viral infections by eliminating infected...
CD8+ T Zellen unterstützen die Beseitigung von Pathogenen und sind somit entscheidend bei der Bekämp...
CD8+ T cell differentiation is a complex process that requires integration of signals from the TCR, ...
Interferon regulatory factor 4 (IRF4) has critical roles in immune cell differentiation and function...
During chronic stimulation, CD8+ T cells acquire an exhausted phenotype characterized by expression ...
Interferon regulatory factor 4 (IRF4) has critical roles in immune cell differentiation and function...
During immune responses, T cells are subject to clonal competition, which leads to the predominant e...
TCR signal strength is critical for CD8+ T cell clonal expansion after antigen stimulation. Levels o...
The transcription factor IRF-4 is necessary for Th17 cell differentiation. In this issue of Immunity...
Memory T cells are largely heterogeneous. The molecular mechanisms at the basis of their effector fu...
<div><p>CD8<sup>+</sup> T cell exhaustion commonly occurs in chronic infections and cancers. During ...
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