In this issue of Cancer Cell, Anido et al. demonstrate that Id1 is the likely arbiter of divergent transforming growth factor-β (TGF-β) signaling in glioma-initiating cells (GICs) from different tumors. These findings hold both the promise and potential peril of therapeutic targeting of the TGF-β pathway
SummaryDespite aggressive surgery, radiotherapy, and chemotherapy, treatment of malignant glioma rem...
Cancers may escape elimination by the host immune system by rewiring the tumour microenvironment tow...
Inhibitors of VEGF (vascular endothelial growth factor)/VEGFR2 (vascular endothelial growth factor r...
Tvorogov et al. (2010) describe in this issue of Cancer Cell an antibody that inhibits homodimerizat...
SummaryGlioma-initiating cells (GICs), also called glioma stem cells, are responsible for tumor init...
In this issue of Cancer Cell, Anido et al. demonstrate that Id1 is the likely arbiter of divergent t...
Background: Glioblastoma (GBM) is a highly migratory, invasive, and angiogenic brain tumor. Like vas...
In this issue of Cancer Cell, Lu et al. describe unconventional molecular interactions in glioblasto...
Cancers may escape elimination by the host immune system by rewiring the tumour microenvironment tow...
TGFβ is a pleiotropic cytokine that plays critical roles to define cancer cell phenotypes, construct...
Cancer is driven by numerous cellular dysregulations such as increased proliferation, decreased apop...
A growing body of evidence suggests that only a small subpopulation of malignant glioma cells have t...
We investigated blocking the TGF-b signaling pathway in HCC using two small molecule inhibitors (LY2...
SummaryWhen a cancer escapes the growth-inhibitory effects of TGF-β secreted by cancer cells themsel...
Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The s...
SummaryDespite aggressive surgery, radiotherapy, and chemotherapy, treatment of malignant glioma rem...
Cancers may escape elimination by the host immune system by rewiring the tumour microenvironment tow...
Inhibitors of VEGF (vascular endothelial growth factor)/VEGFR2 (vascular endothelial growth factor r...
Tvorogov et al. (2010) describe in this issue of Cancer Cell an antibody that inhibits homodimerizat...
SummaryGlioma-initiating cells (GICs), also called glioma stem cells, are responsible for tumor init...
In this issue of Cancer Cell, Anido et al. demonstrate that Id1 is the likely arbiter of divergent t...
Background: Glioblastoma (GBM) is a highly migratory, invasive, and angiogenic brain tumor. Like vas...
In this issue of Cancer Cell, Lu et al. describe unconventional molecular interactions in glioblasto...
Cancers may escape elimination by the host immune system by rewiring the tumour microenvironment tow...
TGFβ is a pleiotropic cytokine that plays critical roles to define cancer cell phenotypes, construct...
Cancer is driven by numerous cellular dysregulations such as increased proliferation, decreased apop...
A growing body of evidence suggests that only a small subpopulation of malignant glioma cells have t...
We investigated blocking the TGF-b signaling pathway in HCC using two small molecule inhibitors (LY2...
SummaryWhen a cancer escapes the growth-inhibitory effects of TGF-β secreted by cancer cells themsel...
Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The s...
SummaryDespite aggressive surgery, radiotherapy, and chemotherapy, treatment of malignant glioma rem...
Cancers may escape elimination by the host immune system by rewiring the tumour microenvironment tow...
Inhibitors of VEGF (vascular endothelial growth factor)/VEGFR2 (vascular endothelial growth factor r...
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