AbstractAnimal models of cystic fibrosis, in particular several different mutant mouse strains obtained by homologous recombination, have contributed considerably to our understanding of CF pathology. In this review, we describe and compare the main phenotypic features of these models. Recent and possible future developments in this field are discussed
The leading cause of mortality and morbidity in humans with cystic fibrosis is lung disease. Advance...
Various animal models are available to study cystic fibrosis (CF). These models may help to enhance ...
Animal models of cystic fibrosis (CF) are essential for investigating disease mechanisms and trialin...
AbstractGenetically modified mice have been studied for more than fifteen years as models of cystic ...
Our understanding of the multiorgan pathology of cystic fibrosis (CF) has improved impressively duri...
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulat...
Cystic fibrosis (CF) is the most common fatal autosomal recessive genetic disorder in Caucasian popu...
In humans, cystic fibrosis (CF) lung disease is characterised by chronic infection, inflammation, ai...
textabstractBackground: From the original CftrTgH(neoim)Hgu mutant mouse model with a divergent gene...
The cystic fibrosis (CF) field is the beneficiary of five species of animal models that lack functio...
To develop an animal model for cystic fibrosis (CF), targeted gene disruption in embryonic stem (ES)...
Large animal models of genetic diseases are rapidly becoming integral to biomedical research as tech...
Most cystic fibrosis (CF) patients produce a mutant form (delta F508) of the cystic fibrosis transme...
AbstractChronic lung disease remains the major cause of morbidity and mortality of cystic fibrosis (...
Item does not contain fulltextAnimal models for cystic fibrosis (CF) have enhanced our understanding...
The leading cause of mortality and morbidity in humans with cystic fibrosis is lung disease. Advance...
Various animal models are available to study cystic fibrosis (CF). These models may help to enhance ...
Animal models of cystic fibrosis (CF) are essential for investigating disease mechanisms and trialin...
AbstractGenetically modified mice have been studied for more than fifteen years as models of cystic ...
Our understanding of the multiorgan pathology of cystic fibrosis (CF) has improved impressively duri...
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulat...
Cystic fibrosis (CF) is the most common fatal autosomal recessive genetic disorder in Caucasian popu...
In humans, cystic fibrosis (CF) lung disease is characterised by chronic infection, inflammation, ai...
textabstractBackground: From the original CftrTgH(neoim)Hgu mutant mouse model with a divergent gene...
The cystic fibrosis (CF) field is the beneficiary of five species of animal models that lack functio...
To develop an animal model for cystic fibrosis (CF), targeted gene disruption in embryonic stem (ES)...
Large animal models of genetic diseases are rapidly becoming integral to biomedical research as tech...
Most cystic fibrosis (CF) patients produce a mutant form (delta F508) of the cystic fibrosis transme...
AbstractChronic lung disease remains the major cause of morbidity and mortality of cystic fibrosis (...
Item does not contain fulltextAnimal models for cystic fibrosis (CF) have enhanced our understanding...
The leading cause of mortality and morbidity in humans with cystic fibrosis is lung disease. Advance...
Various animal models are available to study cystic fibrosis (CF). These models may help to enhance ...
Animal models of cystic fibrosis (CF) are essential for investigating disease mechanisms and trialin...