AbstractPreventing ligand-dependent ErbB2 receptor heterodimers by an anti-ErbB2 monoclonal antibody shuts down receptor signaling and has potent antitumor activity even in tumors that express low levels of ErbB2, a finding that could result in a larger number of patients benefiting from anti-ErbB2 therapies
SummaryBreast cancer is still a deadly disease despite major achievements in targeted therapies desi...
The ErbB family of receptor tyrosine kinases plays an important role in the development and pathogen...
active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo- or hetero-dime...
AbstractIn cancer cells, the ErbB2 receptor tyrosine kinase can be activated in two ways: by overexp...
AbstractErbB2 is a ligand-less member of the ErbB receptor family that functions as a coreceptor wit...
The erbB2 oncogene belongs to the type I trans-membrane tyrosine kinase family of receptors. Its med...
The erbB2 oncogene belongs to the type I trans-membrane tyrosine kinase family of receptors. Its med...
The erbB2 oncogene belongs to the type I trans-membrane tyrosine kinase family of receptors. Its med...
Breast cancers are classified into categories according to specific criteria, such as histopathologi...
AbstractA myriad of growth factor-dependent and -independent mechanisms for activating the EGF recep...
The complex of ligand-binding deficient ERBB2 with kinase-dead ERBB3 represents the most potent sign...
AbstractErbB2 is a ligand-less member of the ErbB receptor family that functions as a coreceptor wit...
Cancer is the most fatal disease after cardiovascular disease with over 8.2 million deaths worldwide...
ErbB4 is a member of the ErbB family of receptor tyrosine kinases. The ErbB family also includes EGF...
Ankara : The Department of Molecular Biology and Genetics and the Graduate School of Engineering and...
SummaryBreast cancer is still a deadly disease despite major achievements in targeted therapies desi...
The ErbB family of receptor tyrosine kinases plays an important role in the development and pathogen...
active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo- or hetero-dime...
AbstractIn cancer cells, the ErbB2 receptor tyrosine kinase can be activated in two ways: by overexp...
AbstractErbB2 is a ligand-less member of the ErbB receptor family that functions as a coreceptor wit...
The erbB2 oncogene belongs to the type I trans-membrane tyrosine kinase family of receptors. Its med...
The erbB2 oncogene belongs to the type I trans-membrane tyrosine kinase family of receptors. Its med...
The erbB2 oncogene belongs to the type I trans-membrane tyrosine kinase family of receptors. Its med...
Breast cancers are classified into categories according to specific criteria, such as histopathologi...
AbstractA myriad of growth factor-dependent and -independent mechanisms for activating the EGF recep...
The complex of ligand-binding deficient ERBB2 with kinase-dead ERBB3 represents the most potent sign...
AbstractErbB2 is a ligand-less member of the ErbB receptor family that functions as a coreceptor wit...
Cancer is the most fatal disease after cardiovascular disease with over 8.2 million deaths worldwide...
ErbB4 is a member of the ErbB family of receptor tyrosine kinases. The ErbB family also includes EGF...
Ankara : The Department of Molecular Biology and Genetics and the Graduate School of Engineering and...
SummaryBreast cancer is still a deadly disease despite major achievements in targeted therapies desi...
The ErbB family of receptor tyrosine kinases plays an important role in the development and pathogen...
active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo- or hetero-dime...
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