An age- and blood pressure-associated increase in methylglyoxal (MG) and MG-induced advanced glycation endproducts (AGEs), including Nε-carboxyethyl-lysine (CEL) and Nε-carboxymethyl-lysine (CML), in the kidney of spontaneously hypertensive rats (SHR) has been shown. In the present study, gender-related changes in AGEs and nitric oxide synthase were investigated in Sprague–Dawley (SD) and stroke-prone SHR (SHRsp) rats. Immunohistochemical analyses were conducted on kidneys from 24-week-old male and female SD rats as well as SHRsp. The systolic blood pressure of SHRsp was significantly higher than that of SD rats. Male SD rats had more intense kidney staining for CEL than female SD rats. Both male and female SHRsp had more marked CEL and CML...
The metabolic syndrome is complicated by nephropathy in humans and rats, and males are more affected...
AbstractDahl-Iwai (DI) salt-sensitive rats were studied using microarrays to identify sex-specific d...
sitivity to proteinuria induced by mild NOS inhibition in rats: role of sex hormones. Am J Physiol R...
An age- and blood pressure-associated increase in methylglyoxal (MG) and MG-induced advanced glycati...
Sexual dimorphism in the aging kidney: Effects on injury and nitric oxide system.BackgroundMale gend...
Background-—We previously reported that sexually mature female spontaneously hypertensive rats (SHRs...
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensiv...
Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Spontaneously hypertensive stroke-prone rats (SHRSP) feature an established model for human cerebrov...
Chronic kidney disease (CKD) is considered a public health problem, assuming epidemic proportions wo...
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensiv...
The metabolic syndrome is complicated by nephropathy in humans and rats, and males are more affected...
AbstractDahl-Iwai (DI) salt-sensitive rats were studied using microarrays to identify sex-specific d...
sitivity to proteinuria induced by mild NOS inhibition in rats: role of sex hormones. Am J Physiol R...
An age- and blood pressure-associated increase in methylglyoxal (MG) and MG-induced advanced glycati...
Sexual dimorphism in the aging kidney: Effects on injury and nitric oxide system.BackgroundMale gend...
Background-—We previously reported that sexually mature female spontaneously hypertensive rats (SHRs...
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensiv...
Sex-specific computational models of the spontaneously hypertensive rat kidneys: factors affecting...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Males are at greater risk for renal injury than females. This may relate to nitric oxide (NO) availa...
Spontaneously hypertensive stroke-prone rats (SHRSP) feature an established model for human cerebrov...
Chronic kidney disease (CKD) is considered a public health problem, assuming epidemic proportions wo...
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensiv...
The metabolic syndrome is complicated by nephropathy in humans and rats, and males are more affected...
AbstractDahl-Iwai (DI) salt-sensitive rats were studied using microarrays to identify sex-specific d...
sitivity to proteinuria induced by mild NOS inhibition in rats: role of sex hormones. Am J Physiol R...