A recent Cell paper by He et al. (2009) shows how metformin circumvents a block between insulin and atypical protein kinase C in obese and diabetic mice to inhibit gluconeogenesis by stimulating the phosphorylation of CBP and the disassembly of the CREB transcriptional complex
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
Metformin has been used for nearly a century and is now the most widely prescribed oral anti-diabeti...
Metformin, the first-line drug to treat type 2 diabetes (T2D), inhibits mitochondrial glycerolphosph...
A recent Cell paper by He et al. (2009) shows how metformin circumvents a block between insulin and ...
SummaryInsulin resistance and elevated glucagon levels result in nonsuppressible hepatic glucose pro...
SummaryInsulin resistance and elevated glucagon levels result in nonsuppressible hepatic glucose pro...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
The liver is a main target tissue of the biguanide metformin which activates AMP-activated protein k...
pages 1-15International audienceMetformin is widely used to treat hyperglycemia in individuals with ...
pages 1-15International audienceMetformin is widely used to treat hyperglycemia in individuals with ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
pages 1-15International audienceMetformin is widely used to treat hyperglycemia in individuals with ...
The liver is a main target tissue of the biguanide metformin which activates AMP-activated protein k...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
Metformin has been used for nearly a century and is now the most widely prescribed oral anti-diabeti...
Metformin, the first-line drug to treat type 2 diabetes (T2D), inhibits mitochondrial glycerolphosph...
A recent Cell paper by He et al. (2009) shows how metformin circumvents a block between insulin and ...
SummaryInsulin resistance and elevated glucagon levels result in nonsuppressible hepatic glucose pro...
SummaryInsulin resistance and elevated glucagon levels result in nonsuppressible hepatic glucose pro...
Metformin, developed from an ancient herbal remedy, remains the front-line drug for treatment of typ...
The liver is a main target tissue of the biguanide metformin which activates AMP-activated protein k...
pages 1-15International audienceMetformin is widely used to treat hyperglycemia in individuals with ...
pages 1-15International audienceMetformin is widely used to treat hyperglycemia in individuals with ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
pages 1-15International audienceMetformin is widely used to treat hyperglycemia in individuals with ...
The liver is a main target tissue of the biguanide metformin which activates AMP-activated protein k...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
7 pagesInternational audienceAlthough considerable efforts have been made since the 1950s to better ...
Metformin has been used for nearly a century and is now the most widely prescribed oral anti-diabeti...
Metformin, the first-line drug to treat type 2 diabetes (T2D), inhibits mitochondrial glycerolphosph...
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