Active zones are the sites of neurotransmitter release, but their assembly mechanisms are poorly understood. In this issue of Neuron, Graf et al. perform a genetic screen in Drosophila and uncover a novel role for the Rab3 GTPase in organizing the active zone at the neuromuscular junction
We are interested in understanding the molecular mechanisms that govern synaptic growth and plastici...
Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have par...
Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling p...
Active zones are the sites of neurotransmitter release, but their assembly mechanisms are poorly und...
SummarySynaptic transmission requires the localization of presynaptic release machinery to active zo...
<div><p>At synapses, the release of neurotransmitter is regulated by molecular machinery that aggreg...
At synapses, the release of neurotransmitter is regulated by molecular machinery that aggregates at ...
SummaryBackgroundNeurons require highly specialized intracellular membrane trafficking, especially a...
Synaptic transmission requires the localization of presynaptic release machinery to active zones. Me...
SummaryHomeostatic signaling systems stabilize neural function through the modulation of neurotransm...
Funding:This work was supported by H2020-GA661543-Neuronal Trafficking (ROT), IF/00392/2013/ CP1192/...
AbstractRecent analysis of Rho subfamily GTPases in Drosophila revealed roles for Rac and Cdc42 duri...
Background: Neurons require highly specialized intracellular membrane trafficking, especially at syn...
The active zone (AZ) protein Bruchpilot (Brp) is essential for rapid glutamate release at Drosophila...
Neuronal communication across synapses relies on neurotransmitter release from presynaptic active zo...
We are interested in understanding the molecular mechanisms that govern synaptic growth and plastici...
Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have par...
Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling p...
Active zones are the sites of neurotransmitter release, but their assembly mechanisms are poorly und...
SummarySynaptic transmission requires the localization of presynaptic release machinery to active zo...
<div><p>At synapses, the release of neurotransmitter is regulated by molecular machinery that aggreg...
At synapses, the release of neurotransmitter is regulated by molecular machinery that aggregates at ...
SummaryBackgroundNeurons require highly specialized intracellular membrane trafficking, especially a...
Synaptic transmission requires the localization of presynaptic release machinery to active zones. Me...
SummaryHomeostatic signaling systems stabilize neural function through the modulation of neurotransm...
Funding:This work was supported by H2020-GA661543-Neuronal Trafficking (ROT), IF/00392/2013/ CP1192/...
AbstractRecent analysis of Rho subfamily GTPases in Drosophila revealed roles for Rac and Cdc42 duri...
Background: Neurons require highly specialized intracellular membrane trafficking, especially at syn...
The active zone (AZ) protein Bruchpilot (Brp) is essential for rapid glutamate release at Drosophila...
Neuronal communication across synapses relies on neurotransmitter release from presynaptic active zo...
We are interested in understanding the molecular mechanisms that govern synaptic growth and plastici...
Rab GTPases are molecular switches that regulate membrane trafficking in all cells. Neurons have par...
Techniques to induce activity-dependent neuronal plasticity in vivo allow the underlying signaling p...