Melanocyte Stem Cell Maintenance and Hair Graying
- Steingrímsson, Eiríkur
- Copeland, Neal G.
- Jenkins, Nancy A.
Publication date
April 2005
DOI Publisher
Elsevier Inc. ISSN
0092-8674 Citation count (estimate)
76Abstract
Hair graying is an obvious sign of human aging, yet little was known about its causes. Two recent papers provide compelling evidence that hair graying is due to incomplete melanocyte stem cell maintenance and identify Pax3 and Mitf as key molecules that help regulate the balance between melanocyte stem cell maintenance and differentiation
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