AbstractClC chloride channels orchestrate the movement of chloride necessary for proper neuronal, muscular, cardiovascular, and epithelial function. In this issue of Neuron, Jentsch, Pusch, and colleagues use the structure of a bacterial ClC homolog to guide a mutagenic analysis of inhibitor binding to ClC-0, ClC-1, and ClC-2
ClC-2 is a broadly distributed chloride channel with an enigmatic neurophysiological function. In th...
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby ...
AbstractClC chloride channels and transporters play major roles in cellular excitability, epithelial...
AbstractClC chloride channels orchestrate the movement of chloride necessary for proper neuronal, mu...
AbstractMembers of the ClC family of voltage-gated chloride channels are found from bacteria to mamm...
The voltage-dependent ClC-1 chloride channel belongs to the CLC channel/transporter family. It is a ...
AbstractCrystal structures of bacterial CLC proteins were solved recently, but it is unclear to whic...
AbstractSeveral plasma membrane chloride channels are well characterized, but much less is known abo...
CLC anion transporters are found in all phyla and form a gene family of eight members in mammals. Tw...
Abstract: CLC proteins are a nine-member gene family of Cl- channels that have diverse roles in the ...
Molecular mechanisms of ion conduction in ClC-type chloride channels: Lessons from disease-causing m...
Cl- channels reside both in the plasma membrane and in intracellular organelles. Their functions ran...
The ClC family of chloride channels are found throughout the eukaryotes and homologues are found amo...
After a personal description of the convoluted path leading 25 years ago to the molecular identifica...
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby ...
ClC-2 is a broadly distributed chloride channel with an enigmatic neurophysiological function. In th...
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby ...
AbstractClC chloride channels and transporters play major roles in cellular excitability, epithelial...
AbstractClC chloride channels orchestrate the movement of chloride necessary for proper neuronal, mu...
AbstractMembers of the ClC family of voltage-gated chloride channels are found from bacteria to mamm...
The voltage-dependent ClC-1 chloride channel belongs to the CLC channel/transporter family. It is a ...
AbstractCrystal structures of bacterial CLC proteins were solved recently, but it is unclear to whic...
AbstractSeveral plasma membrane chloride channels are well characterized, but much less is known abo...
CLC anion transporters are found in all phyla and form a gene family of eight members in mammals. Tw...
Abstract: CLC proteins are a nine-member gene family of Cl- channels that have diverse roles in the ...
Molecular mechanisms of ion conduction in ClC-type chloride channels: Lessons from disease-causing m...
Cl- channels reside both in the plasma membrane and in intracellular organelles. Their functions ran...
The ClC family of chloride channels are found throughout the eukaryotes and homologues are found amo...
After a personal description of the convoluted path leading 25 years ago to the molecular identifica...
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby ...
ClC-2 is a broadly distributed chloride channel with an enigmatic neurophysiological function. In th...
ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby ...
AbstractClC chloride channels and transporters play major roles in cellular excitability, epithelial...