Sutureless Anastomoses of Small and Medium Sized Vessels by Medical Adhesive

AbstractPurposeUsing an animal model we have assessed sutureless anastomoses.MethodsThe two cut ends of the rabbit common carotid artery were sutured by three stitches with a 120° interval circumferentially, then two optional threads were pulled horizontally and 0.1ml adhesive was smeared on the attached surface of the two ends. The three stitches were removed after completion of anastomosis. The burst pressure of the anastomosis was measured and compared with that of a traditional sutured artery.ResultsThe glued anastomosis was associated with: a shorter completion time (8.25±6.34min vs. 20.67±14.24min, P<0.01), less bleeding (3.17±9.04ml vs. 11.04±16.28ml, P<0.01), and equivalent patency (93.8 vs. 87.5%, P>0.05). The sutureless anastomosis was associated with less intimal thickening (decreased by 31.4, 24.5, 23.9 and 31.9%, P