SummaryNew studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications
Background: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while...
SummaryHuman embryonic stem cells (hESCs) expressing pluripotency markers are assumed to possess equ...
Thanks to well-established quantitative functional assays and prospective isolation methods, hematop...
SummaryNew studies suggest that stem cells of embryonic, neural, and hematopoietic origin are hetero...
peer reviewedPluripotency can be considered a functional characteristic of pluripotent stem cells (P...
BACKGROUND: Commitment in embryonic stem cells is often depicted as a binary choice between alternat...
BACKGROUND:Commitment in embryonic stem cells is often depicted as a binary choice between alternate...
Reports of heterogeneity within embryonic stem cell lines suggest that pluripotent stem cells captur...
Background: Commitment in embryonic stem cells is often depicted as a binary choice between alternat...
Fluctuating expression of transcription factors in embryonic stem cells is an alluring observation, ...
Human embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos. O...
Background: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while...
Cellular heterogeneity is now considered an inherent property of most stem cell types, including plu...
Pluripotent stem cells display significant heterogeneity in gene expression, but whether this divers...
The mechanism by which an apparently uniform population of cells can generate a heterogeneous popula...
Background: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while...
SummaryHuman embryonic stem cells (hESCs) expressing pluripotency markers are assumed to possess equ...
Thanks to well-established quantitative functional assays and prospective isolation methods, hematop...
SummaryNew studies suggest that stem cells of embryonic, neural, and hematopoietic origin are hetero...
peer reviewedPluripotency can be considered a functional characteristic of pluripotent stem cells (P...
BACKGROUND: Commitment in embryonic stem cells is often depicted as a binary choice between alternat...
BACKGROUND:Commitment in embryonic stem cells is often depicted as a binary choice between alternate...
Reports of heterogeneity within embryonic stem cell lines suggest that pluripotent stem cells captur...
Background: Commitment in embryonic stem cells is often depicted as a binary choice between alternat...
Fluctuating expression of transcription factors in embryonic stem cells is an alluring observation, ...
Human embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos. O...
Background: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while...
Cellular heterogeneity is now considered an inherent property of most stem cell types, including plu...
Pluripotent stem cells display significant heterogeneity in gene expression, but whether this divers...
The mechanism by which an apparently uniform population of cells can generate a heterogeneous popula...
Background: Embryonic stem cells (ESC) have the capacity to self-renew and remain pluripotent, while...
SummaryHuman embryonic stem cells (hESCs) expressing pluripotency markers are assumed to possess equ...
Thanks to well-established quantitative functional assays and prospective isolation methods, hematop...