AbstractAmong the numerous steroid and orphan nuclear receptors encoded within mammalian genomes, several are involved in regulating immune system functions. We review here recent studies on the glucocorticoid receptor and the orphan receptors Nur77 and RORγ. These molecules play key roles in the development and the effector functions of T lymphocytes
LRH-1 (liver receptor homolog-1/NR5a2) is an orphan nuclear receptor, which regulates glucose and li...
C1 - Journal Articles RefereedT lymphocytes (pivotal in many inflammatory pathologies) are targets f...
Neurohypophysial oxytocin (OT) and vasopressin (VP) genes are transcribed in thymic epithelium, whil...
AbstractThe transcription factor Nur77, an orphan member of the nuclear hormone receptor superfamily...
AbstractWe have identified RORγt, a novel, thymus-specific isoform of the orphan nuclear receptor RO...
Thymocytes differentiate into mature T cells with an immunological restriction for self major histoc...
Nr4a1-3 encode a small family of orphan nuclear hormone receptors with transcriptional activity. The...
International audienceRORγt is a nuclear hormone receptor that has followed an exponential success c...
Glucocorticoids (GCs) are a class of steroid hormones which regulate a variety of essential biologic...
The nuclear receptor Nur77 is expressed in a multitude of tissues, regulating cell differentiation a...
AbstractNuclear receptors (NRs) have recently received much attention for their newly discovered rol...
The nuclear receptor (NR) superfamily is composed of 48 members in humans and includes receptors for...
As an essential safeguard against autoimmunity, apoptosis during negative selection of self-reactive...
The orphan nuclear receptor Nur77 is an immediate-early response gene that based on tissue and cell ...
Apoptosis, or programmed cell death, occurs in response to various biological signals, providing a m...
LRH-1 (liver receptor homolog-1/NR5a2) is an orphan nuclear receptor, which regulates glucose and li...
C1 - Journal Articles RefereedT lymphocytes (pivotal in many inflammatory pathologies) are targets f...
Neurohypophysial oxytocin (OT) and vasopressin (VP) genes are transcribed in thymic epithelium, whil...
AbstractThe transcription factor Nur77, an orphan member of the nuclear hormone receptor superfamily...
AbstractWe have identified RORγt, a novel, thymus-specific isoform of the orphan nuclear receptor RO...
Thymocytes differentiate into mature T cells with an immunological restriction for self major histoc...
Nr4a1-3 encode a small family of orphan nuclear hormone receptors with transcriptional activity. The...
International audienceRORγt is a nuclear hormone receptor that has followed an exponential success c...
Glucocorticoids (GCs) are a class of steroid hormones which regulate a variety of essential biologic...
The nuclear receptor Nur77 is expressed in a multitude of tissues, regulating cell differentiation a...
AbstractNuclear receptors (NRs) have recently received much attention for their newly discovered rol...
The nuclear receptor (NR) superfamily is composed of 48 members in humans and includes receptors for...
As an essential safeguard against autoimmunity, apoptosis during negative selection of self-reactive...
The orphan nuclear receptor Nur77 is an immediate-early response gene that based on tissue and cell ...
Apoptosis, or programmed cell death, occurs in response to various biological signals, providing a m...
LRH-1 (liver receptor homolog-1/NR5a2) is an orphan nuclear receptor, which regulates glucose and li...
C1 - Journal Articles RefereedT lymphocytes (pivotal in many inflammatory pathologies) are targets f...
Neurohypophysial oxytocin (OT) and vasopressin (VP) genes are transcribed in thymic epithelium, whil...