The prodiginine antibiotics exhibit antitumor and immunosuppressive activity. In this issue of Chemistry & Biology, Reynolds and coworkers [1] demonstrate that new prodiginines can be obtained by substituting a FabH ketosynthase for the RedP ketosynthase in the undecylprodiginine biosynthetic gene cluster
Prodigiosin synthetase PigC is an ATP-dependent membrane-associated ligase that catalyzes the final ...
AbstractIn this issue of Chemistry & Biology, a novel priming mechanism is proposed for aromatic pol...
Bacterial secondary metabolites have historically been a rich source of antibiotic compounds. The ge...
Background: Prodiginines are a large family of pigmented oligopyrrole antibiotics with medicinal pot...
Background: Prodiginines are a large family of pigmented oligopyrrole antibiotics with medicinal pot...
SummaryThe enzyme RedP is thought to initiate the biosynthesis of the undecylpyrolle component of th...
SummaryThe red gene cluster of Streptomyces coelicolor directs production of undecylprodiginine. Her...
AbstractThe biosynthetic gene cluster for the pluramycin-type antitumor antibiotic hedamycin has bee...
Natural products are essential to the discovery of new drugs, including antibiotics. Industrial inte...
The growing demand to fulfill the needs of present-day medicine in terms of novel effective molecule...
Natural products are a well-established source of drugs, and evolution has yielded polyketides such ...
Prodiginines are a large family of red-pigmented antibiotics produced by a range of actinomycetes an...
AbstractThe polyketide vicenistatin has significant anticancer activity. In the January issue of Che...
Prodigiosin ligase PigC catalyses the final condensation step in the prodigiosin biosynthesis of Ser...
Antimycins are anticancer compounds produced by a hybrid nonribosomal peptide synthetase/polyketide ...
Prodigiosin synthetase PigC is an ATP-dependent membrane-associated ligase that catalyzes the final ...
AbstractIn this issue of Chemistry & Biology, a novel priming mechanism is proposed for aromatic pol...
Bacterial secondary metabolites have historically been a rich source of antibiotic compounds. The ge...
Background: Prodiginines are a large family of pigmented oligopyrrole antibiotics with medicinal pot...
Background: Prodiginines are a large family of pigmented oligopyrrole antibiotics with medicinal pot...
SummaryThe enzyme RedP is thought to initiate the biosynthesis of the undecylpyrolle component of th...
SummaryThe red gene cluster of Streptomyces coelicolor directs production of undecylprodiginine. Her...
AbstractThe biosynthetic gene cluster for the pluramycin-type antitumor antibiotic hedamycin has bee...
Natural products are essential to the discovery of new drugs, including antibiotics. Industrial inte...
The growing demand to fulfill the needs of present-day medicine in terms of novel effective molecule...
Natural products are a well-established source of drugs, and evolution has yielded polyketides such ...
Prodiginines are a large family of red-pigmented antibiotics produced by a range of actinomycetes an...
AbstractThe polyketide vicenistatin has significant anticancer activity. In the January issue of Che...
Prodigiosin ligase PigC catalyses the final condensation step in the prodigiosin biosynthesis of Ser...
Antimycins are anticancer compounds produced by a hybrid nonribosomal peptide synthetase/polyketide ...
Prodigiosin synthetase PigC is an ATP-dependent membrane-associated ligase that catalyzes the final ...
AbstractIn this issue of Chemistry & Biology, a novel priming mechanism is proposed for aromatic pol...
Bacterial secondary metabolites have historically been a rich source of antibiotic compounds. The ge...
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