Health-related quality of life in acute myeloid leukaemia and multiple myeloma survivors undergoing autologous progenitor stem cell transplantation: a retrospective analysis

SummaryBackgroundHaematopoietic stem cell transplantation (HSCT) is a specific therapeutic method used for biomodulation antitumour therapy of haematological malignancies and of solid tumours. It is also used for the therapy of non-tumour and hereditary diseases.AimTo analyse the selected psychosocial, health and demographic aspects of quality of life (QoL) in acute myeloid leukaemia (AML) and multiple myeloma (MM) survivors undergoing autologous progenitor stem cell transplantation (PSCT).Materials/MethodsThe total number of AML survivors was 12 (7 male, 5 female). The total number of MM survivors was 32 (18 male, 14 female). The average age of AML survivors was 47.5 years old. Average age of MM survivors was 60 years old. The Czech version of the international generic European Quality of Life Questionnaire, Version EQ-5D, was used. The effect of selected psychosocial, health and demographic aspects of QoL was determined by means of analysis of variance. The descriptive analysis was used for evaluation of QoL questionnaires.ResultsThe above-mentioned aspects proved statistically significant dependence of QoL (EQ-5D score and EQ-5D VAS) on age in both cohorts (p<0.01), religion in AML cohort (p<0.05), smoking abuse in both cohorts (p<0.01), level of education in AML cohort (p<0.05), increasing number of associated diseases in both cohorts (p<0.05) and type of disease (p