A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition
- Loverdos, Ines
- Swan, Marc C.
- Shekherdimian, Shant
- Al-Rasheed, Abdulrahman A.
- Schneider, Rayfel
- Fish, Joel S.
- Ngan, Bo-Yee
- Adeli, Khosrow
- Lowe, Mark E.
- Singh, Vijay P.
- Sevilla, Wednesday Marie A.
- Langer, Jacob C.
- Gonska, Tanja
Publication date
May 2015
DOI Publisher
The Authors. Published by Elsevier Inc. ISSN
2213-5766 Citation count (estimate)
4Abstract
AbstractPancreatitis-Panniculitis-Polyarthritis (PPP) syndrome is rare and its physiopathology unclear. A 6-year old boy suffered of traumatic pancreatitis complicated by PPP syndrome. Extensive investigations demonstrated high levels of pancreatic lipase and fatty acids in the affected peripheral tissues. These findings support the sequence of peripheral lipolysis and fatty acid accumulation inducing tissue inflammation
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