The posttranslational modification of proteins by methylglyoxal, a highly reactive compound derived from glycolysis, may contribute to aging, diabetes, and other disorders. In this issue of Cell, Brownlee and colleagues (Yao et al., 2006) demonstrate a specific mechanism by which methylglyoxal modifies a transcriptional corepressor to enhance gene expression
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matr...
AMPA-type glutamate receptors (AMPARs) are ligand-gated cationic channels formed from combinations o...
The c-Myc proto-oncogene is an essential activator of cell proliferation and one of the genes most c...
Destruction of intact cellular proteins is largely orchestrated by ATP-dependent ubiquitination and ...
The protein tyrosine phosphatase PTP1B, previously recognized for its role in downregulating insulin...
Skin, the largest organ of our body, is often plagued by cancer because of exposure to ultraviolet r...
Linker histones of the H1 family are among the most abundant components of chromatin. In this issue ...
In this issue of Cell, Grunewald et al. (2006) examine the role of hematopoietic cells in the format...
SummaryMicroorganisms growing on surfaces can form biofilms under certain conditions. In this issue ...
The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transf...
Understanding the molecular mechanisms that control the architecture of organelles is an area of int...
The nuclear protein kinase ATR is a key regulator of genome integrity that functions at checkpoints ...
Both cellular differentiation and stem cell maintenance must occur at the root apex in order to ensu...
The death receptor ligand TRAIL has shown remarkable promise as an anticancer agent. However, TRAIL ...
O2 deprivation (hypoxia) and cellular proliferation engage opposite cellular pathways, yet often coe...
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matr...
AMPA-type glutamate receptors (AMPARs) are ligand-gated cationic channels formed from combinations o...
The c-Myc proto-oncogene is an essential activator of cell proliferation and one of the genes most c...
Destruction of intact cellular proteins is largely orchestrated by ATP-dependent ubiquitination and ...
The protein tyrosine phosphatase PTP1B, previously recognized for its role in downregulating insulin...
Skin, the largest organ of our body, is often plagued by cancer because of exposure to ultraviolet r...
Linker histones of the H1 family are among the most abundant components of chromatin. In this issue ...
In this issue of Cell, Grunewald et al. (2006) examine the role of hematopoietic cells in the format...
SummaryMicroorganisms growing on surfaces can form biofilms under certain conditions. In this issue ...
The PML protein induces senescence, and, upon oncogenic stress, its absence promotes cellular transf...
Understanding the molecular mechanisms that control the architecture of organelles is an area of int...
The nuclear protein kinase ATR is a key regulator of genome integrity that functions at checkpoints ...
Both cellular differentiation and stem cell maintenance must occur at the root apex in order to ensu...
The death receptor ligand TRAIL has shown remarkable promise as an anticancer agent. However, TRAIL ...
O2 deprivation (hypoxia) and cellular proliferation engage opposite cellular pathways, yet often coe...
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matr...
AMPA-type glutamate receptors (AMPARs) are ligand-gated cationic channels formed from combinations o...
The c-Myc proto-oncogene is an essential activator of cell proliferation and one of the genes most c...
DOI
Add to ORKG