The integration of chromatin modifiers into specific regulatory networks is not fully understood. In this issue of Immunity, Austenaa et al. (2012) demonstrate a specific role for the histone methyltransferase MLL4 (Wbp7) in controlling the expression of critical molecules in the Toll-like receptor pathway
AbstractDNase I hypersensitivity assays and phylogenetic analyses previously led to the identificati...
In the mammalian gastrointestinal tract, distinct types of cells, including epithelial cells and mac...
The cells of the innate immune system are responsible for the first line of defense against foreign ...
SummaryHistone methyltransferases catalyze site-specific deposition of methyl groups, enabling recru...
Transcription of the Class II genes of the Major Histocompatibility Complex (MHCII) requires a compl...
The immune system is exquisitely poised to identify, respond to, and eradicate pathogens from the bo...
SIGNIFICANCE: A growing body of clinical and experimental evidence has challenged the traditional un...
The induction of trained immunity represents an emerging concept defined as the ability of innate im...
© 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND ...
In the periphery, T helper cell differentiation is a key event orchestrating the adaptive immune res...
Waves of changes in genome structure in immune response. 京都大学プレスリリース. 2019-02-21.Background: The imp...
SummaryThe molecular mechanisms that regulate the rapid transcriptional changes that occur during cy...
Toll-like receptors are a family of pattern recognition receptors (PRRs), which have evolved to reco...
Human innate immune cells exposed to certain infections or stimuli develop enhanced immune responses...
Immune cells develop endotoxin tolerance (ET) after prolonged stimulation. ET increases the level of...
AbstractDNase I hypersensitivity assays and phylogenetic analyses previously led to the identificati...
In the mammalian gastrointestinal tract, distinct types of cells, including epithelial cells and mac...
The cells of the innate immune system are responsible for the first line of defense against foreign ...
SummaryHistone methyltransferases catalyze site-specific deposition of methyl groups, enabling recru...
Transcription of the Class II genes of the Major Histocompatibility Complex (MHCII) requires a compl...
The immune system is exquisitely poised to identify, respond to, and eradicate pathogens from the bo...
SIGNIFICANCE: A growing body of clinical and experimental evidence has challenged the traditional un...
The induction of trained immunity represents an emerging concept defined as the ability of innate im...
© 2020 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND ...
In the periphery, T helper cell differentiation is a key event orchestrating the adaptive immune res...
Waves of changes in genome structure in immune response. 京都大学プレスリリース. 2019-02-21.Background: The imp...
SummaryThe molecular mechanisms that regulate the rapid transcriptional changes that occur during cy...
Toll-like receptors are a family of pattern recognition receptors (PRRs), which have evolved to reco...
Human innate immune cells exposed to certain infections or stimuli develop enhanced immune responses...
Immune cells develop endotoxin tolerance (ET) after prolonged stimulation. ET increases the level of...
AbstractDNase I hypersensitivity assays and phylogenetic analyses previously led to the identificati...
In the mammalian gastrointestinal tract, distinct types of cells, including epithelial cells and mac...
The cells of the innate immune system are responsible for the first line of defense against foreign ...
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