The heterogeneous heat stress response of Escherichia coli K12

AbstractWhen subjected to a temperature increase surpassing the maximum growth temperature (Tmax) Escherichia coli K12 MG1655 populations react heterogeneously, i.e. a sensitive and a resistant population seem to exist. The influence of heat stress adaptation on the model parameters of a heterogeneous model is quantified. In the conditions under study, the growth rate of the resistant population was affected only at the higher temperatures. For the sensitive subpopulation, Tmax,S, as described by the CTMI model, seemed to be influenced, with an increasing maximum growth temperature at a higher heating rate