SummaryMucosal innate lymphoid cell (ILC) subsets promote immune responses to pathogens by producing distinct signature cytokines in response to changes in the cytokine microenvironment. We previously identified human ILC3 distinguished by interleukin-22 (IL-22) secretion. Here we characterized a human ILC1 subset that produced interferon-γ (IFN-γ) in response to IL-12 and IL-15 and had a unique integrin profile, intraepithelial location, hallmarks of TGF-β imprinting, and a memory-activated phenotype. Because tissue-resident memory CD8+ T cells share this profile, intraepithelial ILC1 may be their innate counterparts. In mice, intraepithelial ILC1 were distinguished by CD160 expression and required Nfil3- and Tbx21-encoded transcription fa...
Innate Lymphoid Cells (ILCs) control tissue and metabolic homeostasis, but also provide protection f...
Until a decade ago, natural killer (NK) cells constituted the major—if not the sole—player of innate...
A breakdown of intestinal homeostasis due to dysregulated immune responses against intestinal bacter...
SummaryMucosal innate lymphoid cell (ILC) subsets promote immune responses to pathogens by producing...
Innate lymphoid cells (ILCs) are effectors of innate immunity and regulators of tissue modeling. Rec...
The mechanisms that guide the development of mucosal-associated innate lymphoid cells (ILCs) produci...
Type 3 innate lymphoid cells (ILCs) mediate tissue homeostasis and protection, primarily at mucosal ...
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal ...
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal ...
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal ...
Innate lymphoid cells (ILCs) are a recently described group of innate immune cells that can regulate...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasse...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasse...
Abstract Although group 3 innate lymphoid cells (ILC3s) are efficient inducers of T cell response...
International audienceGroup 3 innate lymphoid cells (ILC3) actively participate in mucosal defense a...
Innate Lymphoid Cells (ILCs) control tissue and metabolic homeostasis, but also provide protection f...
Until a decade ago, natural killer (NK) cells constituted the major—if not the sole—player of innate...
A breakdown of intestinal homeostasis due to dysregulated immune responses against intestinal bacter...
SummaryMucosal innate lymphoid cell (ILC) subsets promote immune responses to pathogens by producing...
Innate lymphoid cells (ILCs) are effectors of innate immunity and regulators of tissue modeling. Rec...
The mechanisms that guide the development of mucosal-associated innate lymphoid cells (ILCs) produci...
Type 3 innate lymphoid cells (ILCs) mediate tissue homeostasis and protection, primarily at mucosal ...
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal ...
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal ...
The Ly49E receptor is preferentially expressed on murine innate-like lymphocytes, such as epidermal ...
Innate lymphoid cells (ILCs) are a recently described group of innate immune cells that can regulate...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasse...
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine that encompasse...
Abstract Although group 3 innate lymphoid cells (ILC3s) are efficient inducers of T cell response...
International audienceGroup 3 innate lymphoid cells (ILC3) actively participate in mucosal defense a...
Innate Lymphoid Cells (ILCs) control tissue and metabolic homeostasis, but also provide protection f...
Until a decade ago, natural killer (NK) cells constituted the major—if not the sole—player of innate...
A breakdown of intestinal homeostasis due to dysregulated immune responses against intestinal bacter...