Antiapoptotic Bcl-2 proteins on mitochondria inhibit prodeath proteins, such as Bax, which are found primarily in the cytosol. In this issue, Edlich et al., (2011) show that Bax and Bcl-xL interact on the mitochondrial surface and then retrotranslocate to the cytosol, effectively preventing Bax-induced permeabilization of mitochondria
The rapid, typically all-or-none process of mitochondrial outer membrane permeabilization (MOMP) con...
The proteins of the Bcl-2 family are key regulators of apoptosis. They form a complex interaction ne...
The proteins of the Bcl-2 family are key regulators of apoptosis. They form a complex interaction ne...
SummaryThe Bcl-2 family member Bax translocates from the cytosol to mitochondria, where it oligomeri...
Antiapoptotic Bcl-2 proteins on mitochondria inhibit prodeath proteins, such as Bax, which are found...
AbstractProtein–protein interactions between the Bcl2 family proteins regulate apoptosis. An imbalan...
The Bcl-2 family protein Bax is a key effector of apoptosis. Lovell et al. (2008) now describe the r...
SummaryThe Bcl-2 family member Bax translocates from the cytosol to mitochondria, where it oligomeri...
AbstractBcl-2 family proteins regulate the release of proteins like cytochrome c from mitochondria d...
AbstractThe localization and control of Bcl-2 proteins on mitochondria is essential for the intrinsi...
Background: Bcl-2 family proteins are key regulators of mitochondrial integrity and comprise both pr...
Background: Bcl-2 family proteins are key regulators of mitochondrial integrity and comprise both pr...
The Bcl-2 family member Bax translocates from the cytosol to mitochondria, where it oligomerizes and...
Bax, a pro-apoptotic member of the Bcl-2 family, is a cytosolic protein that inserts into mitochondr...
Mitochondria were known to play a central role in apoptosis. Specifically, releases of cytochrome c ...
The rapid, typically all-or-none process of mitochondrial outer membrane permeabilization (MOMP) con...
The proteins of the Bcl-2 family are key regulators of apoptosis. They form a complex interaction ne...
The proteins of the Bcl-2 family are key regulators of apoptosis. They form a complex interaction ne...
SummaryThe Bcl-2 family member Bax translocates from the cytosol to mitochondria, where it oligomeri...
Antiapoptotic Bcl-2 proteins on mitochondria inhibit prodeath proteins, such as Bax, which are found...
AbstractProtein–protein interactions between the Bcl2 family proteins regulate apoptosis. An imbalan...
The Bcl-2 family protein Bax is a key effector of apoptosis. Lovell et al. (2008) now describe the r...
SummaryThe Bcl-2 family member Bax translocates from the cytosol to mitochondria, where it oligomeri...
AbstractBcl-2 family proteins regulate the release of proteins like cytochrome c from mitochondria d...
AbstractThe localization and control of Bcl-2 proteins on mitochondria is essential for the intrinsi...
Background: Bcl-2 family proteins are key regulators of mitochondrial integrity and comprise both pr...
Background: Bcl-2 family proteins are key regulators of mitochondrial integrity and comprise both pr...
The Bcl-2 family member Bax translocates from the cytosol to mitochondria, where it oligomerizes and...
Bax, a pro-apoptotic member of the Bcl-2 family, is a cytosolic protein that inserts into mitochondr...
Mitochondria were known to play a central role in apoptosis. Specifically, releases of cytochrome c ...
The rapid, typically all-or-none process of mitochondrial outer membrane permeabilization (MOMP) con...
The proteins of the Bcl-2 family are key regulators of apoptosis. They form a complex interaction ne...
The proteins of the Bcl-2 family are key regulators of apoptosis. They form a complex interaction ne...
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