Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular details of their assembly are poorly understood. Several recent papers identify structural features that drive granule assembly, shedding light on how phase transitions functionally organize the cell and may lead to pathological protein aggregation
Cells compartmentalize biochemical reactions using organelles. Organelles can be either membrane-bou...
P granules and other RNA/protein bodies are membrane-less organelles that may assemble by intracellu...
Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase t...
Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular de...
Cells assemble large, non-membrane bound granules of protein and RNA, termed Ri- bonucleoprotein gra...
SummaryEukaryotic cells contain assemblies of RNAs and proteins termed RNA granules. Many proteins w...
International audienceLiquid-liquid phase separation is thought to be a key organizing principle in ...
Compartmentalization in cells is central to the spatial and temporal control of biochemistry. In add...
Subcellular compartmentalization allows the organization of complex biochemical reactions in space a...
Condensation, or liquid-like phase separation, is a phenomenon indispensable for the spatiotemporal ...
RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein aggregates or...
Protein domains biased toward a few amino acid types are vital for the formation of biomolecular con...
Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces and regula...
P granules are non-membrane-bound RNA-protein compartments that are involved in germline development...
SummaryEukaryotic cells contain membrane-less organelles, including nucleoli and stress granules, th...
Cells compartmentalize biochemical reactions using organelles. Organelles can be either membrane-bou...
P granules and other RNA/protein bodies are membrane-less organelles that may assemble by intracellu...
Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase t...
Nonmembrane-bound organelles such as RNA granules behave like dynamic droplets, but the molecular de...
Cells assemble large, non-membrane bound granules of protein and RNA, termed Ri- bonucleoprotein gra...
SummaryEukaryotic cells contain assemblies of RNAs and proteins termed RNA granules. Many proteins w...
International audienceLiquid-liquid phase separation is thought to be a key organizing principle in ...
Compartmentalization in cells is central to the spatial and temporal control of biochemistry. In add...
Subcellular compartmentalization allows the organization of complex biochemical reactions in space a...
Condensation, or liquid-like phase separation, is a phenomenon indispensable for the spatiotemporal ...
RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein aggregates or...
Protein domains biased toward a few amino acid types are vital for the formation of biomolecular con...
Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces and regula...
P granules are non-membrane-bound RNA-protein compartments that are involved in germline development...
SummaryEukaryotic cells contain membrane-less organelles, including nucleoli and stress granules, th...
Cells compartmentalize biochemical reactions using organelles. Organelles can be either membrane-bou...
P granules and other RNA/protein bodies are membrane-less organelles that may assemble by intracellu...
Just like all matter, proteins can also switch between gas, liquid and solid phases. Protein phase t...
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