Aging Stem Cells: Transcriptome Meets Epigenome Meets Methylome
- Tümpel, Stefan
- Rudolph, K. Lenhard
Publication date
May 2014
DOI Publisher
Elsevier Inc. ISSN
1934-5909 Citation count (estimate)
1Abstract
Aging is associated with impairments in hematopoietic stem cell (HSC) function and an increased risk of leukemogenesis. In this issue of Cell Stem Cell, Sun et al. (2014) use highly purified HSCs along with an integrated genomic approach to evaluate aging-associated alterations in the epigenome and transcriptome of HSCs
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