Patients with severe aplastic anemia (SAA) over 40 years of age are often not offered treatment with hematopoietic cell transplantation (HCT) because of concerns about treatment-related morbidity or mortality. To evaluate this risk, we analyzed outcomes after allogeneic HCT from HLA-identical sibling donors for all older patients with SAA at our center since 1988. The 23 consecutive patients ranged in age from 40 to 68 years. The conditioning regimen was cyclophosphamide (200 mg/kg) and horse antithymocyte globulin. Methotrexate and cyclosporine were given for postgrafting immunosuppression. The cumulative incidences of grades II, III, and IV acute graft-versus-host-disease were 30%, 4%, and 0%, respectively; that for chronic GVHD was 26%. ...
AbstractAs older patients are eligible for allogeneic hematopoietic cell transplantation (HCT), olde...
AbstractAllogeneic hematopoietic stem cell transplantation (HSCT) can achieve durable remissions in ...
Through the recruitment of immunologic mechanisms, allogeneic hematopoeitic cell transplantation (HC...
Patients with severe aplastic anemia (SAA) over 40 years of age are often not offered treatment with...
We report on 499 patients with severe aplastic anemia aged >/= 50years who underwent hematopoietic c...
We report on 499 patients with severe aplastic anemia aged >= 50 years who underwent hematopoietic c...
We report on 499 patients with severe aplastic anemia aged ≥ 50 years who underwent hematopoietic ce...
Survival after allogeneic hematopoietic cell transplantation (HSCT) for severe aplastic anemia (SAA)...
Survival after allogeneic hematopoietic cell transplantation (HSCT) for severe aplastic anemia (SAA)...
We analyzed the outcome of 692 patients with severe aplastic anemia (SAA) receiving transplants from...
Although younger age is associated with favorable prognosis in adults undergoing allogeneic hematopo...
BACKGROUND: Transplantation from an HLA-matched sibling is the treatment of choice for young patient...
BackgroundTransplantation from an HLA-matched sibling is the treatment of choice for young patients ...
Contains fulltext : 202835.pdf (publisher's version ) (Open Access)We report on 49...
Purpose of review Survival outcomes from haematopoietic stem cell transplantation (HSCT) in severe a...
AbstractAs older patients are eligible for allogeneic hematopoietic cell transplantation (HCT), olde...
AbstractAllogeneic hematopoietic stem cell transplantation (HSCT) can achieve durable remissions in ...
Through the recruitment of immunologic mechanisms, allogeneic hematopoeitic cell transplantation (HC...
Patients with severe aplastic anemia (SAA) over 40 years of age are often not offered treatment with...
We report on 499 patients with severe aplastic anemia aged >/= 50years who underwent hematopoietic c...
We report on 499 patients with severe aplastic anemia aged >= 50 years who underwent hematopoietic c...
We report on 499 patients with severe aplastic anemia aged ≥ 50 years who underwent hematopoietic ce...
Survival after allogeneic hematopoietic cell transplantation (HSCT) for severe aplastic anemia (SAA)...
Survival after allogeneic hematopoietic cell transplantation (HSCT) for severe aplastic anemia (SAA)...
We analyzed the outcome of 692 patients with severe aplastic anemia (SAA) receiving transplants from...
Although younger age is associated with favorable prognosis in adults undergoing allogeneic hematopo...
BACKGROUND: Transplantation from an HLA-matched sibling is the treatment of choice for young patient...
BackgroundTransplantation from an HLA-matched sibling is the treatment of choice for young patients ...
Contains fulltext : 202835.pdf (publisher's version ) (Open Access)We report on 49...
Purpose of review Survival outcomes from haematopoietic stem cell transplantation (HSCT) in severe a...
AbstractAs older patients are eligible for allogeneic hematopoietic cell transplantation (HCT), olde...
AbstractAllogeneic hematopoietic stem cell transplantation (HSCT) can achieve durable remissions in ...
Through the recruitment of immunologic mechanisms, allogeneic hematopoeitic cell transplantation (HC...