Peptide ligands destined for binding MHC class I molecules are generated by the proteasome in the cytoplasm and transported to the endoplasmic reticulum for loading onto newly synthesized class I molecules. A new study now provides a quantitative analysis of how total protein turnover in the cell relates to the efficiency of generating peptide epitopes presented by class I molecules
AbstractIntracellular proteins are degraded by the proteasome, and resulting peptides surviving cyto...
AbstractThe fate of peptides that fail to bind to major histocompatibility complex class I molecules...
AbstractAntigenic peptides generated by the proteasome have to survive a peptidase-containing enviro...
Peptide ligands destined for binding MHC class I molecules are generated by the proteasome in the cy...
AbstractUsing L929 cells, we quantitated the macroeconomics of protein synthesis and degradation and...
AbstractThe large set of peptides presented by MHC (major histocompatibility complex) class I molecu...
AbstractThe antigen processing pathway generates the peptides displayed by MHC I molecules on the ce...
SummaryMajor histocompatibility complex (MHC) class I molecules present short, perfectly cleaved pep...
Peptides generated from cellular protein degradation via the ubiquitin-proteasome pathway are presen...
n Abstract Gene-chips contain thousands of nucleotide sequences that allow si-multaneous analysis of...
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC c...
Major histocompatibility complex class I (MHC-1) molecules bind peptide fragments derived from cytos...
Most antigenic peptides presented on MHC class I molecules are generated by proteasomes during prote...
How loading of major histocompatibility complex (MHC) class I-specific peptides by conserved degrada...
Major histocompatibility complex (MHC) class I molecules usually present endogenous peptides at the ...
AbstractIntracellular proteins are degraded by the proteasome, and resulting peptides surviving cyto...
AbstractThe fate of peptides that fail to bind to major histocompatibility complex class I molecules...
AbstractAntigenic peptides generated by the proteasome have to survive a peptidase-containing enviro...
Peptide ligands destined for binding MHC class I molecules are generated by the proteasome in the cy...
AbstractUsing L929 cells, we quantitated the macroeconomics of protein synthesis and degradation and...
AbstractThe large set of peptides presented by MHC (major histocompatibility complex) class I molecu...
AbstractThe antigen processing pathway generates the peptides displayed by MHC I molecules on the ce...
SummaryMajor histocompatibility complex (MHC) class I molecules present short, perfectly cleaved pep...
Peptides generated from cellular protein degradation via the ubiquitin-proteasome pathway are presen...
n Abstract Gene-chips contain thousands of nucleotide sequences that allow si-multaneous analysis of...
Processing of endogenously synthesized proteins generates short peptides that are presented by MHC c...
Major histocompatibility complex class I (MHC-1) molecules bind peptide fragments derived from cytos...
Most antigenic peptides presented on MHC class I molecules are generated by proteasomes during prote...
How loading of major histocompatibility complex (MHC) class I-specific peptides by conserved degrada...
Major histocompatibility complex (MHC) class I molecules usually present endogenous peptides at the ...
AbstractIntracellular proteins are degraded by the proteasome, and resulting peptides surviving cyto...
AbstractThe fate of peptides that fail to bind to major histocompatibility complex class I molecules...
AbstractAntigenic peptides generated by the proteasome have to survive a peptidase-containing enviro...
DOI
Add to ORKG