AbstractThe first X-ray structure of human carboxylesterase 1 (hCE1) and the structures of hCE1 with drug analogs bound reveal important molecular details of how the drugs cocaine, heroin, and tacrine are metabolized and cleared
Human carboxylesterase 1 (hCE1) is a drug- and endobiotic-processing serine hydrolase that exhibits ...
Human carboxylesterase 1 (hCE1) is the primary carboxylesterase expressed in the liver. This critica...
Cocaine is one of the most reinforcing drugs of abuse and has caused serious medical and social prob...
AbstractThe first X-ray structure of human carboxylesterase 1 (hCE1) and the structures of hCE1 with...
AbstractHuman carboxylesterase 1 (hCE1) is a broad-spectrum bioscavenger that plays important roles ...
Mammalian carboxylesterases are promiscuous enzymes responsible for processing a wide variety of dru...
AbstractHuman carboxylesterase 1 (hCE1) is a broad-spectrum bioscavenger that plays important roles ...
Concomitant i.v. use of cocaine and heroin (“speedballing”) is prevalent among drug-abusing populati...
The organophosphorus nerve agents sarin, soman, tabun, and VX exert their toxic effects by inhibitin...
Organophosphorus (OP) nerve agents are potent toxins that inhibit cholinesterases and produce a rapi...
The processing and elimination of harmful exogenous compounds is important for the successful surviv...
Cocaine abuse is a world-wide public health and social problem without a U.S. Food and Drug Administ...
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-r...
Cocaine mediates its reinforcing and toxic actions through a “loss of function” effect at multiple r...
The purpose of this work was: 1) investigation of cocaine metabolism in association with alcohol int...
Human carboxylesterase 1 (hCE1) is a drug- and endobiotic-processing serine hydrolase that exhibits ...
Human carboxylesterase 1 (hCE1) is the primary carboxylesterase expressed in the liver. This critica...
Cocaine is one of the most reinforcing drugs of abuse and has caused serious medical and social prob...
AbstractThe first X-ray structure of human carboxylesterase 1 (hCE1) and the structures of hCE1 with...
AbstractHuman carboxylesterase 1 (hCE1) is a broad-spectrum bioscavenger that plays important roles ...
Mammalian carboxylesterases are promiscuous enzymes responsible for processing a wide variety of dru...
AbstractHuman carboxylesterase 1 (hCE1) is a broad-spectrum bioscavenger that plays important roles ...
Concomitant i.v. use of cocaine and heroin (“speedballing”) is prevalent among drug-abusing populati...
The organophosphorus nerve agents sarin, soman, tabun, and VX exert their toxic effects by inhibitin...
Organophosphorus (OP) nerve agents are potent toxins that inhibit cholinesterases and produce a rapi...
The processing and elimination of harmful exogenous compounds is important for the successful surviv...
Cocaine abuse is a world-wide public health and social problem without a U.S. Food and Drug Administ...
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-r...
Cocaine mediates its reinforcing and toxic actions through a “loss of function” effect at multiple r...
The purpose of this work was: 1) investigation of cocaine metabolism in association with alcohol int...
Human carboxylesterase 1 (hCE1) is a drug- and endobiotic-processing serine hydrolase that exhibits ...
Human carboxylesterase 1 (hCE1) is the primary carboxylesterase expressed in the liver. This critica...
Cocaine is one of the most reinforcing drugs of abuse and has caused serious medical and social prob...
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