Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signaling in HSCs remains unclear. In this issue of Cell Stem Cell, Takubo et al. (2010) and Simsek et al. (2010) demonstrate that hypoxia regulates the metabolic state of HSCs and protects their integrity by controlling HIF-1α
Hematopoietic stem cells (HSCs) are able to self-renew and to differentiate into all blood cells. HS...
Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system a...
SummaryMaintenance and differentiation of hematopoietic stem cells (HSCs) is regulated through cell-...
Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signa...
Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signa...
SummaryHematopoietic stem cells (HSCs) are sustained in a specific microenvironment known as the ste...
Hematopoiesis is the process of blood formation that originates with the hematopoietic stem cell (HS...
Thesis (Ph.D.)--University of Washington, 2017Pluripotent stem cells hold great promise for the futu...
Objective. Recent evidence suggests that hematopoietic stem cells (HSCs) in the bone marrow (BM) are...
Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs...
AbstractEukaryotic organisms require oxygen homeostasis to maintain proper cellular function for sur...
AbstractHypoxia affects many physiologic processes during early stages of mammalian ontogeny, partic...
Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system a...
SummaryHematopoietic stem cells (HSCs) are maintained in hypoxic niches in endosteal regions of bone...
This thesis has studied the role of low oxygen levels, or hypoxia, in hematopoietic stem cells (HSCs...
Hematopoietic stem cells (HSCs) are able to self-renew and to differentiate into all blood cells. HS...
Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system a...
SummaryMaintenance and differentiation of hematopoietic stem cells (HSCs) is regulated through cell-...
Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signa...
Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signa...
SummaryHematopoietic stem cells (HSCs) are sustained in a specific microenvironment known as the ste...
Hematopoiesis is the process of blood formation that originates with the hematopoietic stem cell (HS...
Thesis (Ph.D.)--University of Washington, 2017Pluripotent stem cells hold great promise for the futu...
Objective. Recent evidence suggests that hematopoietic stem cells (HSCs) in the bone marrow (BM) are...
Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs...
AbstractEukaryotic organisms require oxygen homeostasis to maintain proper cellular function for sur...
AbstractHypoxia affects many physiologic processes during early stages of mammalian ontogeny, partic...
Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system a...
SummaryHematopoietic stem cells (HSCs) are maintained in hypoxic niches in endosteal regions of bone...
This thesis has studied the role of low oxygen levels, or hypoxia, in hematopoietic stem cells (HSCs...
Hematopoietic stem cells (HSCs) are able to self-renew and to differentiate into all blood cells. HS...
Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system a...
SummaryMaintenance and differentiation of hematopoietic stem cells (HSCs) is regulated through cell-...
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