Flow cytometry of isolated mitochondria during development and under some pathological conditions

  • Medina, José M
  • López-Mediavilla, Casilda
  • Orfao, Alberto
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Publication date
January 2002
Publisher
Federation of European Biochemical Societies. Published by Elsevier B.V.

Abstract

AbstractMitochondria play an essential role in the generation of the energy needed for eukaryotic cell life and in the release of molecules involved in initiation of cell death. Here we review the changes in isolated mitochondrial fluorescent populations as distinguished by flow cytometry during postnatal development and their regulation by thyroid hormones and catecholamines. The use of flow cytometry in the study of mitochondrial changes occurring under hypothyroidism, alcohol abuse and aging is also reviewed

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