Nascent synaptic networks have a high incidence of silent synapses. In this issue of Neuron, Shen et al. show that a brief burst of action potentials rapidly awaken silent synapses by increasing the availability of synaptic vesicles for fusion through BDNF-triggered presynaptic actin remodeling mediated by the small GTPase Cdc42
AbstractBursts of neuronal activity are transmitted more effectively as synapses mature. However, th...
AbstractThe release of neurotransmitter from nerve terminals occurs at a specialized region of the p...
AbstractWhether contact of an axon with a dendrite is a necessary inductive signal for the assembly ...
Neurons transmit electrical signals as the basis of infor-mation processing in the nervous system. C...
AbstractFormation of glutamatergic synapses entails development of “silent” immature contacts into m...
AbstractThe activation of silent synapses is a proposed mechanism to account for rapid increases in ...
SummaryMaturation of presynaptic transmitter secretion machinery is a critical step in synaptogenesi...
Abstract Silent synapses, defined as structural specializations for neurotransmission that do not pr...
AbstractSlutsky et al. (this issue of Neuron) report that by selectively filtering out low-level unc...
Direct electrophysiological evaluation of ion channels in vertebrate presynaptic nerve terminals has...
AbstractThe spontaneous fusion of vesicles at nerve terminals produces random miniature postsynaptic...
Synaptic plasticity is thought to be integral to learning and memory. The two most common forms of p...
The regulation of synaptic strength is thought to underlie the complex emergent dynamics of neural n...
In adult neurogenesis young neurons connect to the existing network via formation of thousands of ne...
AbstractThe site of modification of synaptic transmission during long-term plasticity in the mammali...
AbstractBursts of neuronal activity are transmitted more effectively as synapses mature. However, th...
AbstractThe release of neurotransmitter from nerve terminals occurs at a specialized region of the p...
AbstractWhether contact of an axon with a dendrite is a necessary inductive signal for the assembly ...
Neurons transmit electrical signals as the basis of infor-mation processing in the nervous system. C...
AbstractFormation of glutamatergic synapses entails development of “silent” immature contacts into m...
AbstractThe activation of silent synapses is a proposed mechanism to account for rapid increases in ...
SummaryMaturation of presynaptic transmitter secretion machinery is a critical step in synaptogenesi...
Abstract Silent synapses, defined as structural specializations for neurotransmission that do not pr...
AbstractSlutsky et al. (this issue of Neuron) report that by selectively filtering out low-level unc...
Direct electrophysiological evaluation of ion channels in vertebrate presynaptic nerve terminals has...
AbstractThe spontaneous fusion of vesicles at nerve terminals produces random miniature postsynaptic...
Synaptic plasticity is thought to be integral to learning and memory. The two most common forms of p...
The regulation of synaptic strength is thought to underlie the complex emergent dynamics of neural n...
In adult neurogenesis young neurons connect to the existing network via formation of thousands of ne...
AbstractThe site of modification of synaptic transmission during long-term plasticity in the mammali...
AbstractBursts of neuronal activity are transmitted more effectively as synapses mature. However, th...
AbstractThe release of neurotransmitter from nerve terminals occurs at a specialized region of the p...
AbstractWhether contact of an axon with a dendrite is a necessary inductive signal for the assembly ...
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