AbstractGraft failure is associated with a high mortality rate. To date, regimens invoked for second transplants have resulted in inconsistent engraftment with high transplant-related mortality (TRM). We here report 16 consecutive patients, aged 4-59 years, who received second HSCT (HSCT-2) at a median of 45 days following primary or secondary failure of an initial unmodified (N = 3) or T cell-depleted (TCD) (N = 13) HSCT (HSCT-1). HSCT-1 was administered after myeloablative total body irradiation (TBI)- or alkylator-based conditioning for acute leukemias (N = 7), MDS (N = 6), CML (N = 2), and Fanconi anemia (N = 1). All patients experienced 1 or more infectious complications between HSCT-1 and HSCT-2, and 10 patients had active infections ...
AbstractDespite the promising data on the outcome of allogeneic stem cell transplantation (SCT) in p...
Haploidentical stem cell transplantation (SCT) has been generally performed using a T cell depleted ...
A fludarabine-based protocol (fludarabine (25 mg/m/day × 6 days), cyclophosphamide (10 mg/kg/day × 2...
AbstractGraft failure is associated with a high mortality rate. To date, regimens invoked for second...
Graft failure is a significant cause of morbidity and mortality after hematopoietic stem cell transp...
AbstractWe investigated whether a novel chemotherapy-alone conditioning regimen would permit durable...
AbstractRecurrent acute myeloid leukemia (AML) after hematopoietic stem cell transplantation (HSCT) ...
We summarized results in 38 consecutive patients (median age=56 years) with hematologic malignancies...
Patients suffering from high-risk myelodysplastic syndrome (MDS) or acute myelogenous leukemia (AML)...
AbstractDespite potent intensive conditioning regimens, hematopoietic stem cell transplantation (HSC...
HLA-mismatched grafts are a viable alternative source for patients without HLA-matched donors receiv...
Background: Results of nonmyeloablative HCT in pts with HLA-mismatched donors have been disappointin...
AbstractReduced-intensity conditioning has extended the use of allogeneic hematopoietic stem cell tr...
Univ Fed Parana, BR-80060000 Curitiba, Parana, BrazilEPM, Inst Oncol Pediat, São Paulo, BrazilEPM, I...
AbstractFifty patients with high-risk hematologic malignancies, underwent an unmanipulated haploiden...
AbstractDespite the promising data on the outcome of allogeneic stem cell transplantation (SCT) in p...
Haploidentical stem cell transplantation (SCT) has been generally performed using a T cell depleted ...
A fludarabine-based protocol (fludarabine (25 mg/m/day × 6 days), cyclophosphamide (10 mg/kg/day × 2...
AbstractGraft failure is associated with a high mortality rate. To date, regimens invoked for second...
Graft failure is a significant cause of morbidity and mortality after hematopoietic stem cell transp...
AbstractWe investigated whether a novel chemotherapy-alone conditioning regimen would permit durable...
AbstractRecurrent acute myeloid leukemia (AML) after hematopoietic stem cell transplantation (HSCT) ...
We summarized results in 38 consecutive patients (median age=56 years) with hematologic malignancies...
Patients suffering from high-risk myelodysplastic syndrome (MDS) or acute myelogenous leukemia (AML)...
AbstractDespite potent intensive conditioning regimens, hematopoietic stem cell transplantation (HSC...
HLA-mismatched grafts are a viable alternative source for patients without HLA-matched donors receiv...
Background: Results of nonmyeloablative HCT in pts with HLA-mismatched donors have been disappointin...
AbstractReduced-intensity conditioning has extended the use of allogeneic hematopoietic stem cell tr...
Univ Fed Parana, BR-80060000 Curitiba, Parana, BrazilEPM, Inst Oncol Pediat, São Paulo, BrazilEPM, I...
AbstractFifty patients with high-risk hematologic malignancies, underwent an unmanipulated haploiden...
AbstractDespite the promising data on the outcome of allogeneic stem cell transplantation (SCT) in p...
Haploidentical stem cell transplantation (SCT) has been generally performed using a T cell depleted ...
A fludarabine-based protocol (fludarabine (25 mg/m/day × 6 days), cyclophosphamide (10 mg/kg/day × 2...