Cell surface dynamics of CFTR: The ins and outs
- Okiyoneda, Tsukasa
- Lukacs, Gergely L.
Publication date
April 2007
DOI Publisher
Published by Elsevier B.V. ISSN
0167-4889 Citation count (estimate)
36Abstract
AbstractGaneshan et al. (Biochem Biophys. Acta 1173 (2007) 192–200) recent study documents the effect of N-WASP inhibition and actin cytoskeleton disruption on the constitutive internalization and recycling of the cystic fibrosis transmembrane conductance regulator (CFTR) channel. The results implicate the cytoskeleton network as a potential modulator of immobilized CFTR pool size at the plasma membrane and the recycling efficiency of endocytosed channel back to the cell surface
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