AbstractTNF's main function is to stimulate inflammation by turning on gene transcription through the IKK/NFκB and JNK/AP-1 signaling cascades. TNF also can trigger apoptosis through caspase-8, but the role and underlying mechanism of this activity are not fully understood. Here, we review recent data on the role of JNK in the regulation of TNF-dependent apoptosis and discuss what is known so far about how cells decide whether to live or die in response to TNF
TNF (Tumor Nekrose Faktor) vermittelt seine biologischen Funktionen durch Interaktionen mit TNFR1 (T...
AbstractThe death domain kinase RIP and the TNF receptor-associated factor 2 (TRAF2) are essential e...
<p>TNF-mediated death and survival pathways are activated following interaction with the TNFRs. The ...
AbstractTNF's main function is to stimulate inflammation by turning on gene transcription through th...
AbstractThrough its type 1 receptor (TNFR1), the cytokine TNF elicits an unusually wide range of bio...
AbstractThrough its type 1 receptor (TNFR1), the cytokine TNF elicits an unusually wide range of bio...
The c-Jun NH2-terminal kinase (JNK) has been implicated in both cell death and survival responses to...
AbstractTumor necrosis factor receptor (TNFR) superfamily members can induce a context-dependent apo...
AbstractTumour necrosis factor-α (TNF) has a variety of cellular effects including apoptotic and nec...
AbstractTRAF2 is believed to mediate the activation of NF-κB and JNK induced by the tumor necrosis f...
AbstractApoptosis induced by TNF-receptor I (TNFR1) is thought to proceed via recruitment of the ada...
Tumor necrosis factor α (TNF-α) binding to the TNF receptor (TNFR) potentially initiates apoptosis a...
Most normal and neoplastic cell types are resistant to tumor necrosis factor (TNF) cytotoxicity unle...
AbstractThe death domain serine/threonine kinase RIP interacts with the death receptors Fas and tumo...
peer reviewedTumour necrosis factor (TNF) is a pro-inflammatory cytokine that has important roles in...
TNF (Tumor Nekrose Faktor) vermittelt seine biologischen Funktionen durch Interaktionen mit TNFR1 (T...
AbstractThe death domain kinase RIP and the TNF receptor-associated factor 2 (TRAF2) are essential e...
<p>TNF-mediated death and survival pathways are activated following interaction with the TNFRs. The ...
AbstractTNF's main function is to stimulate inflammation by turning on gene transcription through th...
AbstractThrough its type 1 receptor (TNFR1), the cytokine TNF elicits an unusually wide range of bio...
AbstractThrough its type 1 receptor (TNFR1), the cytokine TNF elicits an unusually wide range of bio...
The c-Jun NH2-terminal kinase (JNK) has been implicated in both cell death and survival responses to...
AbstractTumor necrosis factor receptor (TNFR) superfamily members can induce a context-dependent apo...
AbstractTumour necrosis factor-α (TNF) has a variety of cellular effects including apoptotic and nec...
AbstractTRAF2 is believed to mediate the activation of NF-κB and JNK induced by the tumor necrosis f...
AbstractApoptosis induced by TNF-receptor I (TNFR1) is thought to proceed via recruitment of the ada...
Tumor necrosis factor α (TNF-α) binding to the TNF receptor (TNFR) potentially initiates apoptosis a...
Most normal and neoplastic cell types are resistant to tumor necrosis factor (TNF) cytotoxicity unle...
AbstractThe death domain serine/threonine kinase RIP interacts with the death receptors Fas and tumo...
peer reviewedTumour necrosis factor (TNF) is a pro-inflammatory cytokine that has important roles in...
TNF (Tumor Nekrose Faktor) vermittelt seine biologischen Funktionen durch Interaktionen mit TNFR1 (T...
AbstractThe death domain kinase RIP and the TNF receptor-associated factor 2 (TRAF2) are essential e...
<p>TNF-mediated death and survival pathways are activated following interaction with the TNFRs. The ...
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