AIM2 was recently implicated in the assembly and activation of the inflammasome in response to eukaryotic and viral dsDNA. Sauer and colleagues (2010) demonstrate that AIM2 is also involved in the activation of the inflammasome in response to the intracellular bacterium Listeria monocytogenes
The innate immune system plays a key role in modulating host immune defense during bacterial disease...
Infection is a dynamic biological process underpinned by a complex interplay between the pathogen an...
Innate immune recognition of microbial components serves as a cornerstone in mediating an effective ...
AIM2 was recently implicated in the assembly and activation of the inflammasome in response to eukar...
Recognition of pathogens and altered self must be efficient and highly specific to orchestrate appro...
Absent in melanoma 2 (AIM2) is a cytosolic DNA sensor which upon activation assembles a multiprotein...
SummaryMicrobial pattern molecules in the intestine play immunoregulatory roles via diverse pattern ...
The inflammasome pathway functions to regulate caspase-1 activation in response to a broad range of ...
Inflammasomes regulate the activity of caspase-1 and the maturation of interleukin 1beta (IL-1beta) ...
Bacterial pneumonia is the leading cause of death in children under the age of five, claiming the li...
The innate immune system senses nucleic acids by germline-encoded pattern recognition receptors. RNA...
Microbial pattern molecules in the intestine play immunoregulatory roles via diverse pattern recogni...
The innate immune system plays a crucial role in the rapid recognition and elimination of invading m...
SummaryThe AIM2 inflammasome is a key cytosolic signaling complex that is activated by double-strand...
Francisella tularensis, the causative agent of tularemia, infects host macrophages, which triggers p...
The innate immune system plays a key role in modulating host immune defense during bacterial disease...
Infection is a dynamic biological process underpinned by a complex interplay between the pathogen an...
Innate immune recognition of microbial components serves as a cornerstone in mediating an effective ...
AIM2 was recently implicated in the assembly and activation of the inflammasome in response to eukar...
Recognition of pathogens and altered self must be efficient and highly specific to orchestrate appro...
Absent in melanoma 2 (AIM2) is a cytosolic DNA sensor which upon activation assembles a multiprotein...
SummaryMicrobial pattern molecules in the intestine play immunoregulatory roles via diverse pattern ...
The inflammasome pathway functions to regulate caspase-1 activation in response to a broad range of ...
Inflammasomes regulate the activity of caspase-1 and the maturation of interleukin 1beta (IL-1beta) ...
Bacterial pneumonia is the leading cause of death in children under the age of five, claiming the li...
The innate immune system senses nucleic acids by germline-encoded pattern recognition receptors. RNA...
Microbial pattern molecules in the intestine play immunoregulatory roles via diverse pattern recogni...
The innate immune system plays a crucial role in the rapid recognition and elimination of invading m...
SummaryThe AIM2 inflammasome is a key cytosolic signaling complex that is activated by double-strand...
Francisella tularensis, the causative agent of tularemia, infects host macrophages, which triggers p...
The innate immune system plays a key role in modulating host immune defense during bacterial disease...
Infection is a dynamic biological process underpinned by a complex interplay between the pathogen an...
Innate immune recognition of microbial components serves as a cornerstone in mediating an effective ...
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