In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Complex 2 promotes the differentiation of T helper 1 (Th1) cells via the kinase Akt, whereas it independently fosters Th2 cell generation via another kinase, PKC-θ
SummaryThe innate inflammatory immune response must be tightly controlled to avoid damage to the hos...
<p>The unique functional attributes possessed by T cells are initiated after stimulation via their T...
As the name indicates, T-helper cells are shown to help in primary and secondary cellular and humora...
In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Comp...
SummaryMany functions of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) have been defin...
The decision of naive Th cells to assume the fate of effector or regulator Th cells heavily influenc...
SummaryEffector T cell differentiation requires the simultaneous integration of multiple, and someti...
SummaryNaive T cells respond to antigen stimulation by exiting from quiescence and initiating clonal...
T cells are an important part of the adaptive immune system and play critical roles in the eliminati...
SummaryThe differentiation of CD4+ helper T cell subsets with diverse effector functions is accompan...
In this issue of Immunity, Shi et al. (2008) identify a previously unknown requirement in T helper c...
AbstractThe T helper lymphocyte is responsible for orchestrating an appropriate immune response to p...
AbstractThe Tec family tyrosine kinase, Itk, is critical for PLC-γ1 activation downstream of the TCR...
SummaryThe mechanisms underpinning integration of instructions that program naive CD8+ T cells for e...
Upon infection, antigen-specific naive CD8 T cells are activated and differentiate into short-lived ...
SummaryThe innate inflammatory immune response must be tightly controlled to avoid damage to the hos...
<p>The unique functional attributes possessed by T cells are initiated after stimulation via their T...
As the name indicates, T-helper cells are shown to help in primary and secondary cellular and humora...
In this issue of Immunity, Lee et al. (2010) demonstrate that the mammalian Target of Rapamycin Comp...
SummaryMany functions of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) have been defin...
The decision of naive Th cells to assume the fate of effector or regulator Th cells heavily influenc...
SummaryEffector T cell differentiation requires the simultaneous integration of multiple, and someti...
SummaryNaive T cells respond to antigen stimulation by exiting from quiescence and initiating clonal...
T cells are an important part of the adaptive immune system and play critical roles in the eliminati...
SummaryThe differentiation of CD4+ helper T cell subsets with diverse effector functions is accompan...
In this issue of Immunity, Shi et al. (2008) identify a previously unknown requirement in T helper c...
AbstractThe T helper lymphocyte is responsible for orchestrating an appropriate immune response to p...
AbstractThe Tec family tyrosine kinase, Itk, is critical for PLC-γ1 activation downstream of the TCR...
SummaryThe mechanisms underpinning integration of instructions that program naive CD8+ T cells for e...
Upon infection, antigen-specific naive CD8 T cells are activated and differentiate into short-lived ...
SummaryThe innate inflammatory immune response must be tightly controlled to avoid damage to the hos...
<p>The unique functional attributes possessed by T cells are initiated after stimulation via their T...
As the name indicates, T-helper cells are shown to help in primary and secondary cellular and humora...
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