Mst1 and Mst2 are key components of the Hippo tumor suppressor pathway. In this issue, Zhou et al. (2009) reported that Mst1/2 ablation leads to hepatocellular carcinomas. Unexpectedly, Mst1/2 may activate another kinase besides Lats1 and Lats2 to phosphorylate YAP, and the role of Mst1/2 in YAP regulation is cell type dependent
The conserved Hippo signaling pathway regulates organ size in Drosophila and mammals. While a core k...
Hippo Tumor Suppressor Pathway is the main pathway for cell growth that regulates tissue enlargement...
The mechanism of body and organ size control is an unsolved puzzle. Recent Drosophila genetics studi...
SummaryHippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We s...
Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We show tha...
The Hippo signaling pathway has been recently elucidated as a tumor suppressor pathway controlling c...
Vicente Valero III,1 Timothy M Pawlik,1 Robert A Anders21Department of Surgery, Division of Surgical...
Cancer therapy and tumor treatment remain unsolved puzzles. Genetic screening for tumor suppressor g...
Hippo pathway, originally discovered in Drosophila, is responsible for organ size control. The pathw...
Abstract Silencing the Hippo kinases mammalian sterile 20‐like 1 and 2 (MST1/2) activates the transc...
Abstract The Hippo pathway regulates cell fate, tipping the scales between proliferation and apoptos...
The Hippo pathway controls organ size and tissue homeostasis by regulating cell proliferation and ap...
As highly conserved signaling cascades of multicellular organisms, Wnt and Hippo pathways control a ...
How organ size is controlled in mammals is not currently understood. In Drosophila the Hippo signali...
Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we obser...
The conserved Hippo signaling pathway regulates organ size in Drosophila and mammals. While a core k...
Hippo Tumor Suppressor Pathway is the main pathway for cell growth that regulates tissue enlargement...
The mechanism of body and organ size control is an unsolved puzzle. Recent Drosophila genetics studi...
SummaryHippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We s...
Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We show tha...
The Hippo signaling pathway has been recently elucidated as a tumor suppressor pathway controlling c...
Vicente Valero III,1 Timothy M Pawlik,1 Robert A Anders21Department of Surgery, Division of Surgical...
Cancer therapy and tumor treatment remain unsolved puzzles. Genetic screening for tumor suppressor g...
Hippo pathway, originally discovered in Drosophila, is responsible for organ size control. The pathw...
Abstract Silencing the Hippo kinases mammalian sterile 20‐like 1 and 2 (MST1/2) activates the transc...
Abstract The Hippo pathway regulates cell fate, tipping the scales between proliferation and apoptos...
The Hippo pathway controls organ size and tissue homeostasis by regulating cell proliferation and ap...
As highly conserved signaling cascades of multicellular organisms, Wnt and Hippo pathways control a ...
How organ size is controlled in mammals is not currently understood. In Drosophila the Hippo signali...
Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we obser...
The conserved Hippo signaling pathway regulates organ size in Drosophila and mammals. While a core k...
Hippo Tumor Suppressor Pathway is the main pathway for cell growth that regulates tissue enlargement...
The mechanism of body and organ size control is an unsolved puzzle. Recent Drosophila genetics studi...
DOI
Add to ORKG