Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae
- Garcı́a-Rodriguez, L.J
- Trilla, J.A
- Castro, C
- Valdivieso, M.H
- Durán, A
- Roncero, C
Publication date
July 2000
DOI Publisher
Federation of European Biochemical Societies. Published by Elsevier B.V. ISSN
0014-5793Abstract
AbstractDeletion of the 1,3-β-D-glucan synthase gene FKS1 in Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of CSIII activity is mainly due to the intracellular delocalization of Chs3p and Chs4p, the two main components of the CSIII active complex
Add to ORKG