AbstractRibonucleases, once dismissed as uninteresting digestive enzymes, have been shown to have remarkable biological activities. Onconase®, from the Northern leopard frog, is currently in clinical trials as a cancer chemotherapeutic. Recent research has revealed some key factors responsible for the cytotoxicity of ribonucleases, and may lead to a new class of drugs
Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or eukaryotic...
Onconase (ONC), a member of the RNase A superfamily extracted from oocytes of Rana pipiens, is an ef...
ABSTRACT: The ribonuclease inhibitor (RI) is a cytosolic protein and a potent inhibitor of bovine pa...
AbstractRibonucleases, once dismissed as uninteresting digestive enzymes, have been shown to have re...
Ribonucleases, once dismissed as uninteresting digestive en-zymes, have been shown to have remarkabl...
Ribonucleases are small basic proteins that have shown remarkable antitumor activity linked to their...
Abstract: Onconase ® (ONC) is an amphibian member of the bovine pancreatic ribonuclease (RNase A) su...
www.biochem.wisc.edu/raines ABSTRACT: Ribonuclease A has been the most studied enzyme of the twentie...
AbstractMany ribonucleases (RNases) are highly cytotoxic. In some cases, they attack selectively mal...
Typical antitumor drugs disrupt the flow of biochemical information from DNA to proteins with the a...
Many ribonucleases (RNases) are highly cytotoxic. In some cases, they attack selectively malignant c...
Onconaseâ (ONC) is a homolog of RNase A that is in clinical trials as a cancer chemotherapeutic agen...
Ribonuclease (RNase) is a type of nuclease that catalyzes degradation of RNA into smaller components...
AbstractHuman pancreatic ribonuclease (RNase 1) is a small secretory protein that catalyzes the clea...
The article dwells on ribonucleases (RNAses) whose cytotoxic activity depends on the enzymatic activ...
Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or eukaryotic...
Onconase (ONC), a member of the RNase A superfamily extracted from oocytes of Rana pipiens, is an ef...
ABSTRACT: The ribonuclease inhibitor (RI) is a cytosolic protein and a potent inhibitor of bovine pa...
AbstractRibonucleases, once dismissed as uninteresting digestive enzymes, have been shown to have re...
Ribonucleases, once dismissed as uninteresting digestive en-zymes, have been shown to have remarkabl...
Ribonucleases are small basic proteins that have shown remarkable antitumor activity linked to their...
Abstract: Onconase ® (ONC) is an amphibian member of the bovine pancreatic ribonuclease (RNase A) su...
www.biochem.wisc.edu/raines ABSTRACT: Ribonuclease A has been the most studied enzyme of the twentie...
AbstractMany ribonucleases (RNases) are highly cytotoxic. In some cases, they attack selectively mal...
Typical antitumor drugs disrupt the flow of biochemical information from DNA to proteins with the a...
Many ribonucleases (RNases) are highly cytotoxic. In some cases, they attack selectively malignant c...
Onconaseâ (ONC) is a homolog of RNase A that is in clinical trials as a cancer chemotherapeutic agen...
Ribonuclease (RNase) is a type of nuclease that catalyzes degradation of RNA into smaller components...
AbstractHuman pancreatic ribonuclease (RNase 1) is a small secretory protein that catalyzes the clea...
The article dwells on ribonucleases (RNAses) whose cytotoxic activity depends on the enzymatic activ...
Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or eukaryotic...
Onconase (ONC), a member of the RNase A superfamily extracted from oocytes of Rana pipiens, is an ef...
ABSTRACT: The ribonuclease inhibitor (RI) is a cytosolic protein and a potent inhibitor of bovine pa...
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