The anchoring fibrils at the dermal-epidermal junction have been well characterized as ultrastructural entities. From their appearance, it was proposed that they fortified the attachment of the epidermis to the dermis. This hypothesized function was strengthened by observations indicating that the anchoring fibrils were abnormal, diminished, or absent from individuals with dystrophic epidermolysis bullosa. Therefore, characterization of the molecular constituents of the anchoring fibrils and their interactions with other basement membrane and dermal components might lead to identification of the gene defects underlying at least some forms of epidermolysis bullosa. Type VII collagen was identified as the protein component of anchoring fibril...
Recent studies indicate that in skin of patients with dystrophic epidermolysis bullosa (EB) inversa,...
Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bull...
Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bull...
The anchoring fibrils at the dermal-epidermal junction have been well characterized as ultrastructur...
Dystrophic epidermolysis bullosa is characterized by various abnormalities of anchoring fibrils, whi...
Expression of collagen VII, a candidate molecule for dystrophic epidermolysis bullosa, was analyzed ...
Skin of patients with severe generalized recessive dystrophic epidermolysis bullosa (SGRDEB) was stu...
Type VII collagen is the major component of anchoring fibrils, structures within basement membranes ...
Recent studies showing that type VII collagen is a component of anchoring fibrils suggests that the ...
The collagen VII gene, COL7A1, is the candidate gene for both the recessive and dominant forms of dy...
Type VII collagen is synthesized and secreted by both human keratinocytes and fibroblasts. Although ...
Studies of the recessive dystrophic form of epidermolysis bullosa (RDEB) have suggested that an abno...
Studies of the recessive dystrophic form of epidermolysis bullosa (RDEB) have suggested that an abno...
Severe mutilating recessive dystrophic epidermolysis bullosa presents with extensive blistering, sca...
We recently demonstrated strong genetic linkage between the type VII collagen gene (COL7A1) and both...
Recent studies indicate that in skin of patients with dystrophic epidermolysis bullosa (EB) inversa,...
Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bull...
Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bull...
The anchoring fibrils at the dermal-epidermal junction have been well characterized as ultrastructur...
Dystrophic epidermolysis bullosa is characterized by various abnormalities of anchoring fibrils, whi...
Expression of collagen VII, a candidate molecule for dystrophic epidermolysis bullosa, was analyzed ...
Skin of patients with severe generalized recessive dystrophic epidermolysis bullosa (SGRDEB) was stu...
Type VII collagen is the major component of anchoring fibrils, structures within basement membranes ...
Recent studies showing that type VII collagen is a component of anchoring fibrils suggests that the ...
The collagen VII gene, COL7A1, is the candidate gene for both the recessive and dominant forms of dy...
Type VII collagen is synthesized and secreted by both human keratinocytes and fibroblasts. Although ...
Studies of the recessive dystrophic form of epidermolysis bullosa (RDEB) have suggested that an abno...
Studies of the recessive dystrophic form of epidermolysis bullosa (RDEB) have suggested that an abno...
Severe mutilating recessive dystrophic epidermolysis bullosa presents with extensive blistering, sca...
We recently demonstrated strong genetic linkage between the type VII collagen gene (COL7A1) and both...
Recent studies indicate that in skin of patients with dystrophic epidermolysis bullosa (EB) inversa,...
Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bull...
Autoantibodies to type VII collagen are characteristic of the blistering diseases epidermolysis bull...