Role of quantitative diffusion weighted imaging in characterization of breast masses

Ibrahim, Yosra Abdelzaher
Habib, Lobna
Deif, Ahmed

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Publication date

September 2015

DOI

10.1016/j.ejrnm.2015.05.006

Publisher

The Authors. Production and hosting by Elsevier B.V.

ISSN

0378-603X

Citation count (estimate)

Abstract

AbstractPurposeTo evaluate the diagnostic accuracy of diffusion-weighted imaging (DWI) in differentiating benign from malignant breast lesions.Patients and methodsForty patients with positive diagnoses at mammography or breast ultrasound were included in this study. Patients were imaged with dynamic contrast enhanced MRI and DWI before biopsy of their breast tumors. Apparent diffusion coefficient (ADC) map was utilized to select the region of interest (ROI) for ADC calculation. DWI was performed using three sets of b value (0, 400, and 800s/mm2).ResultsThe final analysis comprised 40 breast lesions, 18 of which were malignant and 22 were benign. Significant results were obtained between ADC values of benign and malignant lesions (p<0.001). ...