Among its multiple functions, p53 is a critical regulator of TGF-β responses. Sasai et al. (2008) now identify a new p53 inhibitory protein, XFDL156. During embryonic development, this factor is expressed in the ectoderm germ layer and maintains the pluripotency of ectodermal cells by inhibiting TGF-β target genes that promote mesoderm specification
p53 is a protein with many talents. One of the most fundamental is the ability to act as essential g...
Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participa...
During development and tissue homeostasis, cells must integrate different signals. We investigated h...
Among its multiple functions, p53 is a critical regulator of TGF-β responses. Sasai et al. (2008) no...
AbstractThe p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs...
The p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs to regu...
AbstractRecent work in Xenopus embryos reveals an unexpected developmental role for the tumor suppre...
Abstractp63, a homolog of the tumor suppressor p53, is critical for the development and maintenance ...
TGF-beta signaling is essential for development and proliferative homeostasis. During embryogenesis,...
SummaryTGF-β signaling is essential for development and proliferative homeostasis. During embryogene...
SummaryDuring gastrulation of the amphibian embryo, specification of the three germ layers, endo-, e...
The p53 tumor suppressor is the focus of intense investigation. It is considered a latent transcript...
Embryogenesis requires cell-cell communication in which individual cells send and receive signals th...
AbstractThe specification of left–right asymmetry is an evolutionarily conserved developmental proce...
Transforming growth factor-β (TGF-β) is a multifunctional cytokine of key importance for controlling...
p53 is a protein with many talents. One of the most fundamental is the ability to act as essential g...
Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participa...
During development and tissue homeostasis, cells must integrate different signals. We investigated h...
Among its multiple functions, p53 is a critical regulator of TGF-β responses. Sasai et al. (2008) no...
AbstractThe p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs...
The p53 tumor suppressor belongs to a family of proteins that sense multiple cellular inputs to regu...
AbstractRecent work in Xenopus embryos reveals an unexpected developmental role for the tumor suppre...
Abstractp63, a homolog of the tumor suppressor p53, is critical for the development and maintenance ...
TGF-beta signaling is essential for development and proliferative homeostasis. During embryogenesis,...
SummaryTGF-β signaling is essential for development and proliferative homeostasis. During embryogene...
SummaryDuring gastrulation of the amphibian embryo, specification of the three germ layers, endo-, e...
The p53 tumor suppressor is the focus of intense investigation. It is considered a latent transcript...
Embryogenesis requires cell-cell communication in which individual cells send and receive signals th...
AbstractThe specification of left–right asymmetry is an evolutionarily conserved developmental proce...
Transforming growth factor-β (TGF-β) is a multifunctional cytokine of key importance for controlling...
p53 is a protein with many talents. One of the most fundamental is the ability to act as essential g...
Transforming growth factor-β (TGF-β) is a member of a large superfamily of cytokines which participa...
During development and tissue homeostasis, cells must integrate different signals. We investigated h...
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