The reason certain self-antigens are consistently targeted by autoantibodies may be because they are self-adjuvants. Two papers in this issue of Immunity provide important insights into the contribution of Toll-like receptors in systemic autoimmune disease (Berland et al., 2006; Christensen et al., 2006)
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
SummaryToll-like receptor-7 (TLR7) and 9, innate immune sensors for microbial RNA or DNA, have been ...
ealthy individuals are known to harbour self-specific T cells against a variety of immunodominant se...
The reason certain self-antigens are consistently targeted by autoantibodies may be because they are...
Systemic autoimmune disease is characterized by loss of immunologic tolerance to a restricted set of...
SummaryAntibodies (Abs) to RNA- and DNA-containing autoantigens are characteristic of systemic lupus...
Autoimmunity can be triggered by microbial infection. In this context, the discovery of Toll-like re...
In the past few years there has been an increasing appreciation of the importance of Toll-like recep...
SummaryNucleic acid-binding innate immune receptors such as Toll-like receptor 7 (TLR7) and TLR9 hav...
AbstractThe Regulation of TLR7 and TLR9 in the Prevention of AutoimmunityByZachary Robert NewmanDoct...
In this Review we focus on the initiation of autoantibody production and autoantibody pathogenicity,...
Toll-like receptors (TLRs) are a family of pat-tern recognition receptors that have evolved to detec...
Toll-like receptors (TLRs), part of the innate immune system that recognises molecular signatures, a...
International audienceSjögren’s syndrome (SS) is a chronic systemic autoimmune disease that affects ...
SummaryRecognition of nucleic acids as a signature of infection by Toll-like receptors (TLRs) 7 and ...
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
SummaryToll-like receptor-7 (TLR7) and 9, innate immune sensors for microbial RNA or DNA, have been ...
ealthy individuals are known to harbour self-specific T cells against a variety of immunodominant se...
The reason certain self-antigens are consistently targeted by autoantibodies may be because they are...
Systemic autoimmune disease is characterized by loss of immunologic tolerance to a restricted set of...
SummaryAntibodies (Abs) to RNA- and DNA-containing autoantigens are characteristic of systemic lupus...
Autoimmunity can be triggered by microbial infection. In this context, the discovery of Toll-like re...
In the past few years there has been an increasing appreciation of the importance of Toll-like recep...
SummaryNucleic acid-binding innate immune receptors such as Toll-like receptor 7 (TLR7) and TLR9 hav...
AbstractThe Regulation of TLR7 and TLR9 in the Prevention of AutoimmunityByZachary Robert NewmanDoct...
In this Review we focus on the initiation of autoantibody production and autoantibody pathogenicity,...
Toll-like receptors (TLRs) are a family of pat-tern recognition receptors that have evolved to detec...
Toll-like receptors (TLRs), part of the innate immune system that recognises molecular signatures, a...
International audienceSjögren’s syndrome (SS) is a chronic systemic autoimmune disease that affects ...
SummaryRecognition of nucleic acids as a signature of infection by Toll-like receptors (TLRs) 7 and ...
Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease associated with hormonal, environ...
SummaryToll-like receptor-7 (TLR7) and 9, innate immune sensors for microbial RNA or DNA, have been ...
ealthy individuals are known to harbour self-specific T cells against a variety of immunodominant se...
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