AbstractCPEB is a sequence-specific RNA binding protein that regulates translation during vertebrate oocyte maturation. Adult female CPEB knockout mice contained vestigial ovaries that were devoid of oocytes; ovaries from mid-gestation embryos contained oocytes that were arrested at the pachytene stage. Male CPEB null mice also contained germ cells arrested at pachytene. The germ cells from the knockout mice harbored fragmented chromatin, suggesting a possible defect in homologous chromosome adhesion or synapsis. Two CPE-containing synaptonemal complex protein mRNAs, which interact with CPEB in vitro and in vivo, contained shortened poly(A) tails and mostly failed to sediment with polysomes in the null mice. Synaptonemal complexes were not ...
AbstractXGef was isolated in a screen for proteins interacting with CPEB, a regulator of mRNA transl...
The translation of many maternal mRNAs is regulated by dynamic changes in poly(A) tail length. Durin...
CPEB is a sequence-specific RNA binding protein that promotes polyadenylation-induced translation in...
AbstractCPEB is a sequence-specific RNA binding protein that regulates translation during vertebrate...
CPEB is a sequence-specific RNA-binding protein that regulates polyadenylation-induced translation. ...
In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cyto...
AbstractCytoplasmic poly(A) elongation is widely utilized during the early development of many organ...
CPEB is an mRNA-binding protein that stimulates polyadenylation-induced translation of maternal mRNA...
International audienceCPEB (cytoplasmic polyadenylation element-binding protein) is an important reg...
AbstractCytoplasmic polyadenylation-induced mRNA translation is a hallmark of early animal developme...
Translational activation of several dormant mRNAs in vertebrate oocytes is mediated by cytoplasmic p...
AbstractIn maturing mouse oocytes, protein synthesis is required for meiotic maturation subsequent t...
Xenopus laevis oocytes are transcriptionally silent cells that require hormone stimulation for matur...
Cytoplasmic polyadenylation is a conserved mechanism that controls mRNA translation and stability. A...
AbstractThe synthesis and destruction of cyclin B drives mitosis in eukaryotic cells. Cell cycle pro...
AbstractXGef was isolated in a screen for proteins interacting with CPEB, a regulator of mRNA transl...
The translation of many maternal mRNAs is regulated by dynamic changes in poly(A) tail length. Durin...
CPEB is a sequence-specific RNA binding protein that promotes polyadenylation-induced translation in...
AbstractCPEB is a sequence-specific RNA binding protein that regulates translation during vertebrate...
CPEB is a sequence-specific RNA-binding protein that regulates polyadenylation-induced translation. ...
In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cyto...
AbstractCytoplasmic poly(A) elongation is widely utilized during the early development of many organ...
CPEB is an mRNA-binding protein that stimulates polyadenylation-induced translation of maternal mRNA...
International audienceCPEB (cytoplasmic polyadenylation element-binding protein) is an important reg...
AbstractCytoplasmic polyadenylation-induced mRNA translation is a hallmark of early animal developme...
Translational activation of several dormant mRNAs in vertebrate oocytes is mediated by cytoplasmic p...
AbstractIn maturing mouse oocytes, protein synthesis is required for meiotic maturation subsequent t...
Xenopus laevis oocytes are transcriptionally silent cells that require hormone stimulation for matur...
Cytoplasmic polyadenylation is a conserved mechanism that controls mRNA translation and stability. A...
AbstractThe synthesis and destruction of cyclin B drives mitosis in eukaryotic cells. Cell cycle pro...
AbstractXGef was isolated in a screen for proteins interacting with CPEB, a regulator of mRNA transl...
The translation of many maternal mRNAs is regulated by dynamic changes in poly(A) tail length. Durin...
CPEB is a sequence-specific RNA binding protein that promotes polyadenylation-induced translation in...