In this issue of Structure, Yoon and colleagues provide models of a low affinity cytokine common receptor, IL-10R2, in a ternary complex with two class II cytokines and their corresponding ligand-specific receptors, revealing the nature of their promiscuous interactions
Cytokines are well recognized for the pleiotropic nature of their signaling and biological activitie...
The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony stimula...
AbstractSeven members of a family of cytokine-inducible proteins have been identified, a number of w...
In this issue of Structure, Yoon and colleagues provide models of a low affinity cytokine common rec...
SummaryIL-10R2 is a shared cell surface receptor required for the activation of five class 2 cytokin...
Class II cytokine receptors were originally defined on the basis of sequence homologies in the extra...
Class II cytokine receptors are important pleiotropic regulators of the immune system that play a ce...
AbstractCytokine receptors are transmembrane proteins that transmit a signal into the cell upon liga...
Cytokines are secreted soluble peptides that precisely regulate multiple cellular functions. Amongst...
New and exciting developments in the understanding of the interaction between cytokines and their re...
In the past 2-3 years, a number of cytokine receptors have been partly characterized and the cDNAs f...
AbstractType I helical cytokines are ligands for receptors structurally related by a common sequence...
Cytokine signaling is triggered by a hormone-induced receptor aggregation process. IL-13 employs an ...
Cytokines are soluble factors vital for mammalian physiology. Cytokines elicit highly pleiotropic ac...
For the majority of single transmembrane-spanning cell surface receptors, signal transmission across...
Cytokines are well recognized for the pleiotropic nature of their signaling and biological activitie...
The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony stimula...
AbstractSeven members of a family of cytokine-inducible proteins have been identified, a number of w...
In this issue of Structure, Yoon and colleagues provide models of a low affinity cytokine common rec...
SummaryIL-10R2 is a shared cell surface receptor required for the activation of five class 2 cytokin...
Class II cytokine receptors were originally defined on the basis of sequence homologies in the extra...
Class II cytokine receptors are important pleiotropic regulators of the immune system that play a ce...
AbstractCytokine receptors are transmembrane proteins that transmit a signal into the cell upon liga...
Cytokines are secreted soluble peptides that precisely regulate multiple cellular functions. Amongst...
New and exciting developments in the understanding of the interaction between cytokines and their re...
In the past 2-3 years, a number of cytokine receptors have been partly characterized and the cDNAs f...
AbstractType I helical cytokines are ligands for receptors structurally related by a common sequence...
Cytokine signaling is triggered by a hormone-induced receptor aggregation process. IL-13 employs an ...
Cytokines are soluble factors vital for mammalian physiology. Cytokines elicit highly pleiotropic ac...
For the majority of single transmembrane-spanning cell surface receptors, signal transmission across...
Cytokines are well recognized for the pleiotropic nature of their signaling and biological activitie...
The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony stimula...
AbstractSeven members of a family of cytokine-inducible proteins have been identified, a number of w...
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