Implantable Neural Signal Amplifier for Epileptic Seizure Prediction

AbstractThis paper deals with the design of low power low noise Neural signal amplifier for Epileptic Seizure Prediction. The advent of Micro-electro Arrays has driven the need for implantable electronic circuitry to detect those Extracellular neural signals(ENG). We proposed a preamplifier of fully differential LNA with gm boosting in order to enhance the gain as well as reduce the power consumption. Low frequency high pass function has been realized with anti-parallel Diode connected PMOS. Simulation results shows that the input referred noise is 1.24uVrms from 100Hz to 5KHz, mid-band voltage gain of 44.6dB and the power consumption is 18.24uw. The results are validated using Cadence spectre simulator with 180nm technology. Inductive coupled rail-to-rail power supply circuits are discussed with a rectifier circuits. Simulation results shows that this implantable amplifier is suitable for Epileptic seizure prediction