AbstractWe study the question: given a morphism ƒ{(Xn, xn)}→{(Yn, yn)} in the category pro-(Poi nted. Homotopy) where the domain and range are inverse sequences of well-pointed CW complexes, and given that ƒ induces an isomorphism {Xn}→{Yn} in pro-(Homotopy), what additional hypotheses force ƒ to be an isomorphism in pro-(Pointed Homotopy)? Conjecture. If the dimensions of the Yn's are bounded, then ⧸ is an isomorphism in pro-(Pointed Homotopy). We first prove the special case of this conjecture in which dim Yn⩽d<∞ for all n, and lim {HdYn}≠0, Yn being the universal cover of Yn. Then we deal with the general case: we show that there are certain elements of each π1Yn with the properties: (i) these elements commute if and only if ƒ is an isom...