In this issue of Chemistry & Biology, Zhou et al. demonstrate the possibility of effective multiple targeting of HIV infection by using a multifunctional molecule in which an anti-CCR5 receptor aptamer (G-3) is conjugated to an anti-TNPO3 siRNA
Background HIV-1 infection is normally characterized by sustained viral replication and a progressiv...
The bacterial defense system CRISPR (clustered regularly interspaced short palindromic repeats) has ...
Introduction: Efficacy of currently approved anti-HIV drugs is hampered by mutations of the viral en...
In this issue of Chemistry & Biology, Zhou et al. demonstrate the possibility of effective multiple ...
SummaryThe C-C chemokine receptor type 5 (CCR5) is a receptor expressed by T cells and macrophages t...
AbstractNew candidates for development as potential drugs or virucides against HIV-1 infection and A...
This is a copy of an article published in Human Gene Therapy Methods © [2014 [copyright Mary Ann Lie...
BACKGROUND: Despite the remarkable success of highly active antiretroviral therapy (HAART) in loweri...
HIV currently infects 35 million people worldwide and antiretroviral treatments are expensive, lifel...
SummaryPeptide nucleic acids (PNAs) bind duplex DNA in a sequence-specific manner, creating triplex ...
Aptamers are synthetic, single stranded nucleic acids that bind specifically to the target protein. ...
Human immunodeficiency virus type I (HIV-1) is a complex retrovirus, which uses the CD4 receptor and...
. These authors contributed equally to this work. CCR5, a coreceptor for HIV-1 entry, is a major tar...
Advances in biotechnology have led to improving human health with number of novel approaches to miti...
Infection with human immunodeficiency virus type 1 (hiv-1), the retrovirus that causes the acquired ...
Background HIV-1 infection is normally characterized by sustained viral replication and a progressiv...
The bacterial defense system CRISPR (clustered regularly interspaced short palindromic repeats) has ...
Introduction: Efficacy of currently approved anti-HIV drugs is hampered by mutations of the viral en...
In this issue of Chemistry & Biology, Zhou et al. demonstrate the possibility of effective multiple ...
SummaryThe C-C chemokine receptor type 5 (CCR5) is a receptor expressed by T cells and macrophages t...
AbstractNew candidates for development as potential drugs or virucides against HIV-1 infection and A...
This is a copy of an article published in Human Gene Therapy Methods © [2014 [copyright Mary Ann Lie...
BACKGROUND: Despite the remarkable success of highly active antiretroviral therapy (HAART) in loweri...
HIV currently infects 35 million people worldwide and antiretroviral treatments are expensive, lifel...
SummaryPeptide nucleic acids (PNAs) bind duplex DNA in a sequence-specific manner, creating triplex ...
Aptamers are synthetic, single stranded nucleic acids that bind specifically to the target protein. ...
Human immunodeficiency virus type I (HIV-1) is a complex retrovirus, which uses the CD4 receptor and...
. These authors contributed equally to this work. CCR5, a coreceptor for HIV-1 entry, is a major tar...
Advances in biotechnology have led to improving human health with number of novel approaches to miti...
Infection with human immunodeficiency virus type 1 (hiv-1), the retrovirus that causes the acquired ...
Background HIV-1 infection is normally characterized by sustained viral replication and a progressiv...
The bacterial defense system CRISPR (clustered regularly interspaced short palindromic repeats) has ...
Introduction: Efficacy of currently approved anti-HIV drugs is hampered by mutations of the viral en...
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