Fibrillary glomerulopathy: report of a case and review of the literature

AbstractFibrillary or immunotactoid glomerulopathy is a glomerular disease due to nonamyloid fibrillary deposits. It belongs to a category of glomerular diseases that is defined by ultrastructural features of organized deposits of extracellular nonbranching microfibrils within the mesangium and capillary walls of renal glomeruli. Light microscopy findings are so diverse and nondiagnostic that fibrillary glomerulonephritis has been nicknamed the “great mimicker”. Since its first description in 1977, there have been marked controversies regarding diagnostic criteria. We here report a case of fibrillary glomerulonephritis in a 65-year-old patient presenting with nephrotic syndrome and progressive renal impairment. He did not respond to corticosteroid treatment