A randomized, placebo-controlled trial of IGF-1 for delayed graft function: A human model to study postischemic ARF.BackgroundInsulin-like growth factor (IGF-1) has been shown in animal models to accelerate recovery from acute renal failure (ARF). However, a therapeutic trial of recombinant human (rh) IGF-1 in patients with ARF in the intensive care unit (ICU) failed to demonstrate efficacy [1]. Such patients often had multiple organ failure, recurrent renal injury, and a delay of several days before commencing treatment.MethodsTo circumvent these confounding factors, we randomized recipients of cadaveric renal allografts to immediate (<5hours) rhIGF-1 versus placebo therapy (100mg/kg subcutaneously twice a day for 6days). Preliminary obser...
Renal growth hormone—insulin-like growth factor-I system in acute renal failure. The renal growth ho...
Introduction: Delayed Graft Function (DGF) is a common complication of renal transplants and the lon...
Abstract Background Delayed graft function (DGF) is traditionally defined as the requirement for dia...
Multicenter clinical trial of recombinant human insulin-like growth factor I in patients with acute ...
This study evaluated whether recombinant human insulin-like growth factor-I (rhIGF-I) enhances recov...
Early experience with extended use of insulin-like growth factor-1 in advanced chronic renal failure...
Effects of IGF-I on renal function in end-stage chronic renal failure. To determine whether insulin-...
International audienceBackground: In kidney transplantation, the use of Anti-Thymocyte Globulins (AT...
Insulin-like growth factor-I restores microvascular autoregulation in experimental chronic renal fai...
IGF-I binding proteins, IGF-I binding protein mRNA and IGF-I receptor mRNA in rats with acute renal ...
Background: Transplantation of kidneys from deceased donors with acute renal failure (ARF) has been ...
Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acu...
BACKGROUND: Ischaemia-reperfusion injury in kidney transplantation leads to delayed graft function (...
Background The early prediction of delayed graft function (DGF) would facilitate patient management ...
Delayed graft function influences renal function, but not survival.BackgroundIn renal transplantatio...
Renal growth hormone—insulin-like growth factor-I system in acute renal failure. The renal growth ho...
Introduction: Delayed Graft Function (DGF) is a common complication of renal transplants and the lon...
Abstract Background Delayed graft function (DGF) is traditionally defined as the requirement for dia...
Multicenter clinical trial of recombinant human insulin-like growth factor I in patients with acute ...
This study evaluated whether recombinant human insulin-like growth factor-I (rhIGF-I) enhances recov...
Early experience with extended use of insulin-like growth factor-1 in advanced chronic renal failure...
Effects of IGF-I on renal function in end-stage chronic renal failure. To determine whether insulin-...
International audienceBackground: In kidney transplantation, the use of Anti-Thymocyte Globulins (AT...
Insulin-like growth factor-I restores microvascular autoregulation in experimental chronic renal fai...
IGF-I binding proteins, IGF-I binding protein mRNA and IGF-I receptor mRNA in rats with acute renal ...
Background: Transplantation of kidneys from deceased donors with acute renal failure (ARF) has been ...
Initial clinical results of the bioartificial kidney containing human cells in ICU patients with acu...
BACKGROUND: Ischaemia-reperfusion injury in kidney transplantation leads to delayed graft function (...
Background The early prediction of delayed graft function (DGF) would facilitate patient management ...
Delayed graft function influences renal function, but not survival.BackgroundIn renal transplantatio...
Renal growth hormone—insulin-like growth factor-I system in acute renal failure. The renal growth ho...
Introduction: Delayed Graft Function (DGF) is a common complication of renal transplants and the lon...
Abstract Background Delayed graft function (DGF) is traditionally defined as the requirement for dia...