Very little is known about the transcription factor network that regulates the development of intestinal intraepithelial lymphocytes (IELs). In this issue of Immunity, Klose et al. (2014b) and Reis et al. (2014) demonstrate an essential role for T-bet in regulating the CD8αα IEL differentiation program
SummaryT-bet is a critical transcription factor for T helper 1 (Th1) cell differentiation. To study ...
AbstractWe and others have recently identified a CD8 locus enhancer (E8I) that directs expression in...
Tissue-resident intestinal intraepithelial T lymphocytes (T-IEL) patrol the gut and have important r...
Very little is known about the transcription factor network that regulates the development of intest...
SummaryCD8αα+ intraepithelial lymphocytes (IELs) are instrumental in maintaining the epithelial barr...
SummaryThe intestinal epithelium harbors large populations of activated and memory lymphocytes, yet ...
In this issue of Immunity, Wu et al. (2014) report that galectin-9 is required for the formation and...
Medical Research Council (G.L., T.T.M., MR/M003493/1; G.L., J.K.H., MR/K002996/1).Research was also ...
Intestinal TCRb+CD4-CD8b-CD8a+ (CD8aa) IELs alleviate T cell induced colitis and have been suggested...
IL-23 is a key driver of pathogenic Th17 cell responses. It has been suggested that the transcriptio...
We sought to investigate the role of the T-box transcription factors, T-bet and eomesodermin (Eomes)...
T lymphocytes are a critical cellular component of the adaptive immune response. They are generated ...
© 2014 Dr. Lucille Catherine RankinInnate lymphoid cells (ILCs) are key effector cells found at muco...
SummaryInnate immune responses are critical for mucosal immunity. Here we describe an innate lymphoc...
© 2017 Dr. Julia Emiley PrierCD8+ T lymphocytes are specialised cells responsible for immunity to in...
SummaryT-bet is a critical transcription factor for T helper 1 (Th1) cell differentiation. To study ...
AbstractWe and others have recently identified a CD8 locus enhancer (E8I) that directs expression in...
Tissue-resident intestinal intraepithelial T lymphocytes (T-IEL) patrol the gut and have important r...
Very little is known about the transcription factor network that regulates the development of intest...
SummaryCD8αα+ intraepithelial lymphocytes (IELs) are instrumental in maintaining the epithelial barr...
SummaryThe intestinal epithelium harbors large populations of activated and memory lymphocytes, yet ...
In this issue of Immunity, Wu et al. (2014) report that galectin-9 is required for the formation and...
Medical Research Council (G.L., T.T.M., MR/M003493/1; G.L., J.K.H., MR/K002996/1).Research was also ...
Intestinal TCRb+CD4-CD8b-CD8a+ (CD8aa) IELs alleviate T cell induced colitis and have been suggested...
IL-23 is a key driver of pathogenic Th17 cell responses. It has been suggested that the transcriptio...
We sought to investigate the role of the T-box transcription factors, T-bet and eomesodermin (Eomes)...
T lymphocytes are a critical cellular component of the adaptive immune response. They are generated ...
© 2014 Dr. Lucille Catherine RankinInnate lymphoid cells (ILCs) are key effector cells found at muco...
SummaryInnate immune responses are critical for mucosal immunity. Here we describe an innate lymphoc...
© 2017 Dr. Julia Emiley PrierCD8+ T lymphocytes are specialised cells responsible for immunity to in...
SummaryT-bet is a critical transcription factor for T helper 1 (Th1) cell differentiation. To study ...
AbstractWe and others have recently identified a CD8 locus enhancer (E8I) that directs expression in...
Tissue-resident intestinal intraepithelial T lymphocytes (T-IEL) patrol the gut and have important r...
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